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This review summarizes current knowledge about primary care clinician and older adult (65+) perspectives about use of life expectancy to guide cancer screening decisions. Clinicians report operational barriers, uncertainty, and hesitation around use of life expectancy in screening decisions. They recognize it may help them more accurately weigh benefits and harms but are unsure how to estimate life expectancy for individual patients. Older adults face conceptual barriers and are generally unconvinced of the benefits of considering their life expectancy when making screening decisions. Life expectancy will always be a difficult topic for clinicians and patients, but there are advantages to incorporating it in cancer screening decisions. We highlight key takeaways from both clinician and older adult perspectives to guide future research.<\/jats:p>","DOI":"10.1177\/10775587231153269","type":"journal-article","created":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T12:13:11Z","timestamp":1676722391000},"page":"372-385","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Perceived Barriers Among Clinicians and Older Adults Aged 65 and Older Regarding Use of Life Expectancy to Inform Cancer Screening: A Narrative Review and Comparison"],"prefix":"10.1177","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3243-0913","authenticated-orcid":false,"given":"Laura E.","family":"Brotzman","sequence":"first","affiliation":[{"name":"University of Michigan School of Public Health, Ann Arbor, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Zikmund-Fisher","sequence":"additional","affiliation":[{"name":"University of Michigan School of Public Health, Ann Arbor, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,2,18]]},"reference":[{"key":"bibr1-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.17016"},{"key":"bibr2-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1186\/s43058-021-00217-7"},{"key":"bibr3-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-016-3629-y"},{"key":"bibr4-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1177\/10499091211003078"},{"key":"bibr5-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4758"},{"key":"bibr6-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-020-00774-x"},{"issue":"3","key":"bibr7-10775587231153269","first-page":"5","volume":"4","author":"Cavanagh S.","year":"1997","journal-title":"Nurse Researcher"},{"key":"bibr8-10775587231153269","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-159-10-201311190-00005"},{"key":"bibr9-10775587231153269","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21414"},{"key":"bibr10-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2009.06.009"},{"key":"bibr11-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-014-3070-z"},{"key":"bibr12-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2021.10.005"},{"key":"bibr13-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2007.04569.x"},{"key":"bibr14-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2014.12.001"},{"key":"bibr15-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-012-2093-6"},{"key":"bibr16-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1111\/hex.12196"},{"key":"bibr17-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X10378701"},{"key":"bibr18-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4708"},{"key":"bibr19-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X19853516"},{"key":"bibr20-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-7-9"},{"key":"bibr21-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-016-9855-z"},{"key":"bibr22-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2020.08.002"},{"key":"bibr23-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-019-05064-w"},{"key":"bibr24-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2005.41012.x"},{"key":"bibr25-10775587231153269","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2017.09.002"},{"key":"bibr26-10775587231153269","volume":"346","author":"Lee S. 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