{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:35:52Z","timestamp":1777934152188,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T00:00:00Z","timestamp":1149120000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:p>This case report describes the use of palifermin in a multiple myeloma patient with a history of osteonecrosis of the jaw (ONJ) for the prevention of high-dose chemotherapy-induced mucositis. Following the day of autologous stem cell infusion, palifermin was discontinued secondary to adverse events. Specifically, palifermin-associated macroglossia seemed to exacerbate the pain localized in the oral cavity area affected by ONJ, necessitating escalated doses of narcotic analgesics. When contemplating palifermin as a mucosal protectant in a hematopoietic stem cell transplant patient with ONJ, a careful benefit-to-risk assessment is in order to ensure optimal effectiveness without undue harm.<\/jats:p>","DOI":"10.1177\/1078155206070451","type":"journal-article","created":{"date-parts":[[2006,10,26]],"date-time":"2006-10-26T20:51:06Z","timestamp":1161895866000},"page":"119-121","source":"Crossref","is-referenced-by-count":1,"title":["Palifermin in a hematopoietic stem cell transplant patient with osteonecrosis                 of the jaw"],"prefix":"10.1177","volume":"12","author":[{"given":"Leah A","family":"Yageman","sequence":"first","affiliation":[{"name":"Eugene Applebaum College of Pharmacy and Allied Health Professions, Wayne                         State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon M","family":"Cronin","sequence":"additional","affiliation":[{"name":"Karmanos Cancer Institute\/Harper Hospital\/The Detroit Medical Center,                         Wayne State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Peres","sequence":"additional","affiliation":[{"name":"Bone Marrow Transplantation Service, Karmanos Cancer Institute and School                         of Medicine, Wayne State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muneer H","family":"Abidi","sequence":"additional","affiliation":[{"name":"Bone Marrow Transplantation Service, Karmanos Cancer Institute and School                         of Medicine, Wayne State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami B","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Eugene Applebaum College of Pharmacy and Allied Health Professions, Wayne                         State University, Detroit, MI, USA, Karmanos Cancer Institute\/Harper                         Hospital\/The Detroit Medical Center, Wayne State University, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,6,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2005.07.007"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21130"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.02.8670"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041875"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040125"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.02.041"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.10.079"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1078155206070451","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1078155206070451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:12:55Z","timestamp":1777687975000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1078155206070451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1177\/1078155206070451"],"URL":"https:\/\/doi.org\/10.1177\/1078155206070451","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6]]}}}