{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:39:35Z","timestamp":1777934375107,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T00:00:00Z","timestamp":1554163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this study was to investigate the influence of high-dose cytosine arabinoside (HDAC)-containing treatments followed by autologous hematopoietic stem cell transplantation on the survival of patients with mantle cell lymphoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>The data of 27 MCL patients who were followed-up between January 2009 and December 2015 were analyzed retrospectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median age of the patients was 63 (range, 45\u201382) with 22 (81.4%) males and 5 (18.6%) females. Eight of 27 patients were treated with HDAC-containing regimens either as induction or salvage chemotherapy followed by autologous hematopoietic stem cell transplantation (AHSCT). The patients who received HDAC-containing regimen followed by AHSCT were found to have better one-year survival compared to others ( p\u2009=\u20090.03). Median follow-up of patient cohort was 27.6 months and median overall survival (OS) was not reached. The probability of one-year OS for all patients was 76.8%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest that HDAC treatment followed by AHSCT seems to provide the best outcome for young-fit patients presenting with mantle cell lymphoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1078155219841110","type":"journal-article","created":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T02:39:21Z","timestamp":1554259161000},"page":"273-278","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of high-dose cytarabine followed by autologous hematopoietic stem cell transplantation on the outcome of patients with mantle cell lymphoma"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4204-7515","authenticated-orcid":false,"given":"Merih K","family":"\u00c7akar","sequence":"first","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emre","family":"Tekg\u00fcnd\u00fcz","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet S","family":"Dal","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alparslan","family":"Merdin","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Semih","family":"Ba\u015f\u00e7\u0131","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dicle","family":"\u0130skender","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilge","family":"U\u011fur","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filiz","family":"Bekdemir","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jale","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahar U","family":"Ulu","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Bak\u0131rta\u015f","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu\u011f\u00e7e N","family":"Yi\u011feno\u011flu","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikmetullah","family":"Batgi","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali H","family":"Kaya","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dicle","family":"\u0130skender","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fevzi","family":"Altunta\u015f","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Ankara Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital, Hematology Clinic and Bone Marrow Transplantation Unit, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,2]]},"reference":[{"key":"bibr1-1078155219841110","volume-title":"WHO classification of tumors of the haematopietic and lymphoid tissues","author":"Swerdlow 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Alternating courses of 3x CHOP and 3x DHAP plus rituximab followed by a high dose ARA-C containing myeloablative regimen and autologous stem cell transplantation (ASCT) increases overall survival when compared to 6 courses of CHOP plus rituximab followed by myeloablative radiochemotherapy and ASCT in mantle cell lymphoma: final analysis of the MCL Younger Trial of the European Mantle Cell Lymphoma Network (MCL net) [abstract]. In:\n                      Proceedings of the 54th ASH annual meeting and exposition\n                      , Atlanta, GA, December 9\u201311 2012. Washington (DC): American Society of Hematology. 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