{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:40:53Z","timestamp":1777934453035,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Oral cavity malignancies constitute 30% of head and neck cancers. The most common distant metastatic sites of glottic carcinoma are usually lung, liver and bone. Although the cutaneous metastasis of head and cancers have been reported with an incidence of 0.7\u20132.4%, skin metastasis of glottic carcinoma is extremely rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>\n                      A 69-year-old male patient was admitted to the emergency department with hemoptysis, dyspnea, weakness in lower extremities and difficulty in swallowing. There were subcutaneous lesions with a diameter of 2\u20135\u2009cm in the scalp, posterior chest wall, nose and abdomen. In addition, there was an ulcerating, painful mass on the right lateral part of the tongue. The biopsy of lesions on tongue and skin revealed a glottic squamous cell carcinoma with cutaneous metastasis. Management and outcome: The patient was treated with cisplatin 50\u2009mg\/m\n                      <jats:sup>2<\/jats:sup>\n                      on day 1, cetuximab 500\u2009mg\/m\n                      <jats:sup>2<\/jats:sup>\n                      on day 1 and 5-fluorouracil 1000\u2009mg\/m\n                      <jats:sup>2<\/jats:sup>\n                      daily on days 1 and 2, repeated every two\u2009weeks. After the first cycle of chemotherapy, the lesions on the skin regressed and dysphagia improved.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>There are limited data about the incidence, diagnostic measures and treatment modalities of glottic cancer with cutaneous metastasis. Our case could provide an important experience to literature by its atypical presentation and treatment-sensitive nature.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1078155219900782","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T00:07:50Z","timestamp":1581034070000},"page":"1495-1498","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of a glottic squamous cell carcinoma with cutaneous metastasis"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8253-5046","authenticated-orcid":false,"given":"Ali","family":"Alkan","sequence":"first","affiliation":[{"name":"Medical Oncology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Kay\u0131\u015f","sequence":"additional","affiliation":[{"name":"Internal Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan Ya\u015far","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Pathology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sel\u00e7uk","family":"Uyla\u015f","sequence":"additional","affiliation":[{"name":"Medical Oncology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzan","family":"Demir Pekta\u015f","sequence":"additional","affiliation":[{"name":"Dermatology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zge","family":"Oral Tapan","sequence":"additional","affiliation":[{"name":"Chest Diseases, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozan","family":"G\u00f6kdo\u011fan","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9084-2599","authenticated-orcid":false,"given":"G\u00f6rkem","family":"T\u00fcrkkan","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebahat","family":"Gen\u00e7","sequence":"additional","affiliation":[{"name":"Chest Diseases, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zg\u00fcr","family":"Tanr\u0131verdi","sequence":"additional","affiliation":[{"name":"Medical Oncology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University School of Medicine, Mu\u011fla, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,6]]},"reference":[{"key":"bibr1-1078155219900782","first-page":"153","volume":"11","author":"Danic D","year":"2003","journal-title":"Acta Dermatovenerol Croat"},{"key":"bibr2-1078155219900782","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199909)21:6<560::AID-HED10>3.0.CO;2-Q"},{"key":"bibr3-1078155219900782","doi-asserted-by":"crossref","unstructured":"Rahman T, Krishnatreya M, Sarma Aet\u00a0al. \nCutaneous metastasis from squamous carcinoma of the base of tongue. 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