{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:41:10Z","timestamp":1777934470321,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The incidence of acyclovir-induced hypersensitivity is rare. To our knowledge, there are four published case reports of oral acyclovir desensitization in adults. Evidence-based guidelines prompt the use of acyclovir for herpes simplex virus (HSV) prophylaxis and treatment. Literature on the cross-reactivity of structurally similar antiviral agents is conflicting, presenting a clinical challenge when choosing an alternative agent. This is a case of successful acyclovir desensitization in an allogeneic stem cell transplant patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>A 69-year-old female patient, diagnosed with myelodysplastic\/myeloproliferative neoplasm, presented to the hospital for donor mismatch allogeneic bone marrow transplant. The patient reported acyclovir-induced angioedema while receiving treatment for non-complicated herpes zoster (shingles) infection. Management &amp; Outcome: After the acyclovir oral desensitization was conducted in an ICU setting with 1:1 patient-nurse ratio, the patient was successfully started on acyclovir therapy, 800mg by mouth twice daily for HSV prophylaxis with no further complications. Discussion: Oral acyclovir desensitization can provide an option for HSV therapy in patients reporting severe allergy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1078155220959408","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T14:17:09Z","timestamp":1600697829000},"page":"1033-1036","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A case of successful acyclovir desensitization in a bone marrow transplant patient"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1670-9148","authenticated-orcid":false,"given":"Diana C","family":"Andrade","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Memorial Hospital West, Pembroke Pines, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariya","family":"Fatakhova","sequence":"additional","affiliation":[{"name":"Larkin University - College of Pharmacy, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahnaz","family":"Fatteh","sequence":"additional","affiliation":[{"name":"Division of Allergy & Immunology, Memorial Healthcare System, Plantation, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heysu","family":"Rubio-Gomez","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Memorial Healthcare System, Hollywood, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,9,21]]},"reference":[{"key":"bibr1-1078155220959408","volume-title":"Zovirax\u00ae (package insert)","author":"Hi-Tech Pharmacal.","year":"2016"},{"key":"bibr2-1078155220959408","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2003.00199.x"},{"key":"bibr3-1078155220959408","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.06.019"},{"key":"bibr4-1078155220959408","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.10.2010.3392"},{"key":"bibr5-1078155220959408","first-page":"386","volume":"70","author":"Henry RE","year":"1993","journal-title":"Ann Allergy"},{"key":"bibr6-1078155220959408","doi-asserted-by":"publisher","DOI":"10.1136\/sti.77.3.204"},{"key":"bibr7-1078155220959408","doi-asserted-by":"publisher","DOI":"10.14740\/jocmr2772w"},{"key":"bibr8-1078155220959408","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000320"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1078155220959408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1078155220959408","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1078155220959408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:23:45Z","timestamp":1777688625000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1078155220959408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1177\/1078155220959408"],"URL":"https:\/\/doi.org\/10.1177\/1078155220959408","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,21]]}}}