{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:42:33Z","timestamp":1777934553822,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T00:00:00Z","timestamp":1643846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Rituximab is a monoclonal antibody that has shown efficacy in non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), both as a single agent and in combination with traditional chemotherapies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>Here, we present a case wherein a 56-year-old man developed dilated cardiomyopathy following one cycle of rituximab and bendamustine chemotherapy protocol used to treat chronic lymphocytic leukemia. On the fifth day the patient developed hypotensive shock followed closely by the development of cough after two days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Management and outcome<\/jats:title>\n                    <jats:p>The patient was started on carvedilol 3.125\u2005mg, ramipril 2.5\u2005mg, and torsemide 5\u2005mg for treatment of cardiomyopathy. Blood transfusion was necessary for hypotensive shock. Antibiotic regimen was started for sepsis and progressive cough. The patient recovered fully from all the symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This case illustrates the potential for cardiomyopathy with rituximab, particularly in patients with chronic lymphocytic leukemia, and its proposed mechanisms and treatment. The expanding utility of rituximab impels us to increase monitoring and awareness of this serious cardiovascular adverse effect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552221077422","type":"journal-article","created":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T09:19:30Z","timestamp":1643879970000},"page":"1650-1653","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Reversible Cardiomyopathy after Rituximab Treatment in a Chronic Lymphocytic Leukemia Patient"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9591-1506","authenticated-orcid":false,"given":"Nishat","family":"Girkar","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy, Poona College of Pharmacy, Bharati Vidyapeeth University, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"Zaki","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Poona College of Pharmacy, Bharati Vidyapeeth University, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunita","family":"Pawar","sequence":"additional","affiliation":[{"name":"Assistant professor, Poona College of Pharmacy, Bharati Vidyapeeth University, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5981-8080","authenticated-orcid":false,"given":"Priti","family":"Dhande","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Bharati Vidyapeeth University Medical College and Hospital, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,2,3]]},"reference":[{"key":"bibr1-10781552221077422","volume":"3","author":"Albakri A","year":"2019","journal-title":"Internal Medicine and Care"},{"key":"bibr2-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000455"},{"key":"bibr3-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1007\/s12012-017-9429-8"},{"key":"bibr4-10781552221077422","first-page":"ECR23","volume":"91","author":"Seifert G","year":"2006","journal-title":"Haematologica"},{"key":"bibr5-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.013777"},{"key":"bibr6-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1177\/1179546819866445"},{"key":"bibr7-10781552221077422","doi-asserted-by":"publisher","DOI":"10.4103\/ijdd.ijdd_64_19"},{"key":"bibr8-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603776"},{"key":"bibr9-10781552221077422","doi-asserted-by":"publisher","DOI":"10.2174\/157340311799960681"},{"key":"bibr10-10781552221077422","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2014.931954"},{"key":"bibr11-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-208203"},{"key":"bibr12-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1159\/000091416"},{"key":"bibr13-10781552221077422","doi-asserted-by":"publisher","DOI":"10.15171\/jrip.2017.04"},{"key":"bibr14-10781552221077422","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080209"},{"key":"bibr15-10781552221077422","doi-asserted-by":"publisher","DOI":"10.3402\/ecrj.v2.27178"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552221077422","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10781552221077422","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552221077422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:26:34Z","timestamp":1777688794000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10781552221077422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,3]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1177\/10781552221077422"],"URL":"https:\/\/doi.org\/10.1177\/10781552221077422","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,3]]}}}