{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:42:31Z","timestamp":1777934551346,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Consumption of complementary and alternative medicine (CAM) is widely described in cancer patient. However, their composition is not clearly defined and the proofs of safety or effectiveness are quite low. We reported here the case of a CAM-induced hepatitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>A 33-years-old men with Non-Small Cell Lung Cancer and treated by combination of immunotherapy and chemotherapy developed hepatitis during 5 months. Viral and iatrogenic etiologies were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Management and outcome<\/jats:title>\n                    <jats:p>Medication reconciliation found concomitant utilisation of CAM. Some of the plants which composed CAM were found to be possible hepatotoxic. After discontinuation of this CAM, liver fonctions normalized. Close monitoring of liver function showed no other hepatitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>CAM induced hepatotoxicity was suspected. Medication reconciliation included CAM is needed in cancer patient to detect drug interactions and CAM side effects to improve cancer patient management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552221090481","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T01:17:06Z","timestamp":1651195026000},"page":"1926-1929","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A case of hepatitis induced by herbal medicine in non-small cell lung cancer patient treated by a combination of immunotherapy and chemotherapy"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-6282","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Lopes","sequence":"first","affiliation":[{"name":"Pharmacy Sterilization Department, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dory","family":"Anne","sequence":"additional","affiliation":[{"name":"Pharmacy Sterilization Department, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0736-7510","authenticated-orcid":false,"given":"Pamart","family":"Guillaume","sequence":"additional","affiliation":[{"name":"Pulmonology Department, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Bruno","sequence":"additional","affiliation":[{"name":"Pharmacy Sterilization Department, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mascaux","family":"C\u00e9line","sequence":"additional","affiliation":[{"name":"Pulmonology Department, Strasbourg University Hospital, Strasbourg, France"},{"name":"Universit\u00e9 de Strasbourg, Inserm UMR_S 1113, IRFAC, Laboratory Streinth (STress REsponse and INnovative THerapy against cancer), ITI InnoVec, 3 avenue Moli\u00e8re 67200 Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gourieux","family":"B\u00e9n\u00e9dicte","sequence":"additional","affiliation":[{"name":"Pharmacy Sterilization Department, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"bibr1-10781552221090481","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-004-0770-7"},{"key":"bibr2-10781552221090481","unstructured":"LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. 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