{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:43:05Z","timestamp":1777934585892,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T00:00:00Z","timestamp":1672012800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Tamoxifen is widely used for the treatment of hormone-responsive breast cancer. In this article, we report a case of a patient who developed hand deformities following long-term administration of tamoxifen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>A 57-year-old woman, followed for invasive ductal carcinoma of the left breast under tamoxifen for 7 years, presenting joint pain with deformities in her fingers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Management &amp; outcome<\/jats:title>\n                    <jats:p>Following the appearance of the adverse effect, tamoxifen was stopped. A series of biologic and radiologic analysis were performed in order to explain the appearance of this event. A substitution treatment was discussed and a rheumatologist's opinion was requested.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Tamoxifen appears to be associated with the development of inflammatory osteoarthritis resembling rheumatoid arthritis. Possible mechanisms of such an effect are discussed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552221147507","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:35:17Z","timestamp":1672101317000},"page":"1246-1250","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Tamoxifen induced hands deformities"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8860-1542","authenticated-orcid":false,"given":"Yasmine","family":"Bendarkawi","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"},{"name":"Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8142-1218","authenticated-orcid":false,"given":"Ali","family":"Cherif Chefchaouni","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"},{"name":"Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sihame","family":"Lkhoyaali","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"},{"name":"Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafsa","family":"Bechar","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"},{"name":"Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4114-3994","authenticated-orcid":false,"given":"Yassine","family":"Boudina","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"},{"name":"Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youssef","family":"Abercha","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"},{"name":"Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Jaouad","family":"Belahcen","sequence":"additional","affiliation":[{"name":"National Institute of Oncology, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Younes","family":"Rahali","sequence":"additional","affiliation":[{"name":"National Institute of Oncology, Ibn Sina University Hospital, Rabat, Morocco"},{"name":"Team of Formulation and Quality Control of Health Products, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,12,26]]},"reference":[{"key":"bibr1-10781552221147507","unstructured":"504-morocco-fact-sheets.pdf [Internet]. [cited 2022 Apr 15]. Available at: https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/504-morocco-fact-sheets.pdf"},{"key":"bibr2-10781552221147507","first-page":"1090","volume":"9","author":"Odermatt R","year":"2013","journal-title":"Swiss Med J"},{"key":"bibr3-10781552221147507","first-page":"73","volume":"30","author":"L\u00f6wy I","year":"2012","journal-title":"Soc Sci Health"},{"key":"bibr4-10781552221147507","unstructured":"RCP - TAMOXIFENE SANDOZ 20 mg, film-coated tablets - 61003801 - BDM ANSM [Internet]. [cited 2022 Apr 15]. Available at: https:\/\/m.base-donnees-publique.medicaments.gouv.fr\/rcp-61003801-1#!rcp-61961476-4."},{"key":"bibr5-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1177\/1078155220915959"},{"key":"bibr6-10781552221147507","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S1297-9589(03)00216-9","volume":"31","author":"Le Bou\u00ebdec G","year":"2003","journal-title":"Gynecology Obstet Fertil"},{"key":"bibr7-10781552221147507","first-page":"2903","volume":"56","author":"Etori S","year":"2017","journal-title":"InternMed"},{"key":"bibr8-10781552221147507","first-page":"522","volume":"21","author":"Ah-Song R","year":"1997","journal-title":"Cancer Detect Prev"},{"key":"bibr9-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1177\/1078155219862342"},{"key":"bibr10-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"bibr11-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.06.116"},{"key":"bibr12-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/33.6.583"},{"key":"bibr13-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"bibr14-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2017-000523"},{"key":"bibr15-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1136\/ard.46.10.777"},{"key":"bibr16-10781552221147507","doi-asserted-by":"publisher","DOI":"10.1016\/j.rhum.2013.01.006"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552221147507","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10781552221147507","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552221147507","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:27:47Z","timestamp":1777688867000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10781552221147507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,26]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1177\/10781552221147507"],"URL":"https:\/\/doi.org\/10.1177\/10781552221147507","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,26]]}}}