{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:43:15Z","timestamp":1777934595612,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T00:00:00Z","timestamp":1680739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Despite depression being a common comorbidity among adults with cancer, limited literature is available regarding pharmacologic depression treatment patterns and predictors in this population. This study aims to examine patterns and predictors of antidepressant prescribing among adults with cancer and depression in ambulatory care settings in the United States (US).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, cross-sectional study utilized data collected from the 2014 to 2015 National Ambulatory Medical Care Survey (NAMCS). The study sample consisted of adults (age\u2009\u2265\u200918 years) with cancer and depression (unweighted N\u2009=\u2009539; weighted N\u2009=\u200911,361,000). A multivariable logistic regression analysis was used to adjust for individual-level factors to identify predictors of antidepressant prescribing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most patients were adults aged\u2009\u2265\u200965 years, female, and non-Hispanic whites. Thirty-seven percent of the study sample received antidepressant treatment. Multivariable logistic regression analysis revealed that race\/ethnicity, physician specialty, and number of medications were significantly associated with receiving antidepressant(s). For example, non-Hispanic whites were two-and-half times more likely to receive an antidepressant [OR 2.43, 95% confidence interval 1.13\u20135.23] compared to other race\/ethnic groups. Every unit increase in the number of prescribed medications increased the likelihood of receiving an antidepressant by 6% (OR 1.06, 95% CI: 1.01\u20131.11).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Among adults with a comorbid cancer and depression diagnosis and a recorded U.S. ambulatory care visit in 2014\u20132015, 37% received antidepressant treatment. This suggests most patients with cancer and depression do not receive pharmacologic treatment for depression. Future studies are needed to investigate the impact of antidepressant treatment on health outcomes in this patient population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552231168598","type":"journal-article","created":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T04:21:30Z","timestamp":1680754890000},"page":"112-119","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Patterns and predictors of antidepressant prescribing among adults with cancer and depression in ambulatory care settings in the United States"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3984-0317","authenticated-orcid":false,"given":"Nina","family":"Vadiei","sequence":"first","affiliation":[{"name":"Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Lopez","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anael","family":"Ponciano","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desiree","family":"Smiley","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"key":"bibr1-10781552231168598","volume-title":"An update on cancer deaths in the United States","author":"Center for Disease Control and Prevention"},{"key":"bibr2-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.39.7372"},{"key":"bibr3-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.11.004"},{"key":"bibr4-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709992285"},{"key":"bibr5-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24561"},{"key":"bibr6-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2793-5"},{"key":"bibr7-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02821-X"},{"key":"bibr8-10781552231168598","doi-asserted-by":"publisher","DOI":"10.2190\/PM.43.4.g"},{"key":"bibr9-10781552231168598","volume-title":"ASCO guidelines: creening, assessment, and care of anxiety and depressive symptoms in adults with cancer*","author":"American Society of Clincal Oncology"},{"key":"bibr10-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3606"},{"key":"bibr11-10781552231168598","volume":"4","author":"Ostuzzi G","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr12-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4286"},{"key":"bibr13-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2016.5057"},{"key":"bibr14-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2010.10040570"},{"key":"bibr15-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.62.4.409"},{"key":"bibr16-10781552231168598","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2021.06.028"},{"key":"bibr17-10781552231168598","doi-asserted-by":"publisher","DOI":"10.2307\/2136779"},{"key":"bibr18-10781552231168598","unstructured":"Survey NAMC. 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