{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:43:45Z","timestamp":1777934625481,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T00:00:00Z","timestamp":1690416000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Autoimmune side effects can be detected during the use of BRAF\/MEK inhibitor. Although its frequency, mechanism and importance are not known exactly, there are cases reported in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>We report a case of drug-induced vitiligo in a patient with metastatic conjunctival malignant melanoma who was treated with BRAF\/MEK inhibition therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Management and Outcome<\/jats:title>\n                    <jats:p>In the case, vitiligo was controlled with topical treatments. Follow-up process of the patient has been continuing with no progression on month 12 of the current treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Although ICI-related autoimmune side effects and vitiligo have been described more frequently, vitiligo may also occur secondary to BRAK\/MEK inhibition. This case also points out that cutaneous toxicity is manageable with no delay in treatment thanks to collaboration of dermatologists and oncologists.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552231189819","type":"journal-article","created":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T18:16:11Z","timestamp":1690481771000},"page":"670-673","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case report: Drug-induced vitiligo during treatment with BRAF\/MEK inhibitors in a patient with metastatic conjunctival melanoma"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5916-6265","authenticated-orcid":false,"given":"Seray","family":"Saray","sequence":"first","affiliation":[{"name":"Bal\u0131kesir Ataturk State Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelin","family":"H\u0131zl\u0131","sequence":"additional","affiliation":[{"name":"Balikesir University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,7,27]]},"reference":[{"key":"e_1_3_2_2_2","article-title":"BRAF and NRAS prognostic values in conjunctival melanoma: analysis and literature review","author":"Valent\u00edn-Bravo FJ","year":"2022","unstructured":"Valent\u00edn-Bravo FJ, et al. BRAF and NRAS prognostic values in conjunctival melanoma: analysis and literature review. 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