{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:43:49Z","timestamp":1777934629634,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:00:00Z","timestamp":1695513600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Canada is in the midst of an overdose crisis. The use of prescription opioids in Canada has increased steadily over the past two decades, with stark increases in opioid-induced respiratory depression and related deaths. Opioids are the mainstay of treatment for cancer-related pain. Patients with cancer are not immune to the risks associated with opioid use but are underrepresented in available literature outlining risk mitigation strategies. Pharmacists are ideally placed to employ opioid risk mitigation practices to support safe and effective opioid use for patients with cancer-related pain. However, the current attitudes, confidence, and safety practices of pharmacists around how to best support these patients are not known.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was a descriptive environmental scan of pharmacists who provide direct patient care in Canada. An electronic questionnaire was built using the web based Opinio software. It was distributed via email by several provincial and national pharmacy organizations and online platforms. The questionnaire consisted of Likert-scale and open-ended questions and was open to participants for a 6-week period from February 12th to March 23rd, 2020. Analysis was conducted using descriptive statistics and qualitative content analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-one responses from pharmacists in nine provinces were included in the analysis. Respondents endorsed limited and varied practices when caring for patients receiving opioids for cancer-related pain. Further, they demonstrated wide ranging confidence and attitudes regarding opioid risk mitigation practices and beliefs. Less than 50% of pharmacists were aware of resources available for their patients with non-medical opioid use, and\/or patients at high risk of opioid-induced respiratory depression. Education, resources, and communication were the most commonly reported perceived facilitators and barriers to resource use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pharmacists in Canada report employing opioid risk mitigation practices with low and varied frequency when caring for patients receiving opioids for cancer-related pain. They endorsed varied confidence and limited awareness of available provider and patient resources. These findings may help inform the development of new education models and evidence-based guidelines. New education models and evidence-based guidelines will support pharmacists in their pharmaceutical care of this vulnerable patient population, ultimately aiming to improve patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552231200169","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T01:30:26Z","timestamp":1695605426000},"page":"1029-1040","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Managing opioids and mitigating opioid risks in patients with cancer: An environmental scan of the attitudes, confidence, and practices of ambulatory, community and hospital pharmacists practicing in Canada"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3953-2042","authenticated-orcid":false,"given":"Erin","family":"MacNeil","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Nova Scotia Health, Nova Scotia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Supportive Care, University Health Network, Toronto, Canada"},{"name":"Department of Family and Community Medicine, University of Toronto, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alissa","family":"Tedesco","sequence":"additional","affiliation":[{"name":"Temmy Latner Centre for Palliative Care, Sinai Health System, Department of Family and Community Medicine, University of Toronto, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roshina","family":"Babaei-Rad","sequence":"additional","affiliation":[{"name":"Centre for Addiction and Mental Health (CAMH), Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Hutton","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Nova Scotia Health, Nova Scotia, Canada"},{"name":"Beatrice Hunter Cancer Research Institute, Halifax, Nova Scotia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,9,24]]},"reference":[{"key":"bibr1-10781552231200169","unstructured":"Canadian Cancer Society. Canadian cancer statistics at a glance. https:\/\/cancer.ca\/en\/research\/cancer-statistics\/cancer-statistics-at-a-glance. (2022, accessed February 27, 2023)."},{"key":"bibr2-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2015.12.340"},{"key":"bibr3-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25761"},{"key":"bibr4-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn419"},{"key":"bibr5-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.0383"},{"key":"bibr6-10781552231200169","unstructured":"World Health Organization. Guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents. Geneva, World Health Organization; 2018. https:\/\/www.who.int\/publications\/i\/item\/9789241550390."},{"key":"bibr7-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.02198"},{"key":"bibr8-10781552231200169","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2019.0038"},{"key":"bibr9-10781552231200169","unstructured":"Government of Canada. Responding to Canada\u2019s opioid overdose crisis. https:\/\/www.canada.ca\/en\/health-canada\/services\/substance-use\/problematic-prescription-drug-use\/opioids\/responding-canada-opioid-crisis.html (2022, accessed 18 Aug 2020)."},{"key":"bibr10-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-018-0143-7"},{"key":"bibr11-10781552231200169","first-page":"71","volume":"7","author":"Carmichael A","year":"2016","journal-title":"Subst Abuse Rehabil"},{"key":"bibr12-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2015-0012"},{"key":"bibr13-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.6789"},{"key":"bibr14-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2014-0071"},{"key":"bibr15-10781552231200169","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol28010086"},{"key":"bibr16-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1177\/106002809402800706"},{"key":"bibr17-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(98)00023-2"},{"key":"bibr18-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.52.4827"},{"key":"bibr19-10781552231200169","unstructured":"Standards of practice for oncology pharmacy in Canada. North Vancouver, BC: Canadian Association of Pharmacy in Oncology. www.capho.org\/standards-practice (2009, accessed 8 August 2020)."},{"key":"bibr20-10781552231200169","unstructured":"Standards of practice: general pharmacy practice. NS: Nova Scotia College of pharmacists. https:\/\/www.nspharmacists.ca\/wp-content\/uploads\/2015\/08\/SOP_PharmacyPracticeGeneral.pdf (2014, accessed 8 August 2020)."},{"key":"bibr21-10781552231200169","unstructured":"Further defining the scope of hematology\/oncology pharmacy practice. Chicago, Il: Hematology\/oncology pharmacy association. https:\/\/www.hoparx.org\/documents\/94\/HOPA18_Scope-2_Web2.pdf (2019, accessed 27 February 2023)."},{"key":"bibr22-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.34392"},{"key":"bibr23-10781552231200169","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-019-00820-8"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552231200169","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10781552231200169","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552231200169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:29:00Z","timestamp":1777688940000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10781552231200169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,24]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1177\/10781552231200169"],"URL":"https:\/\/doi.org\/10.1177\/10781552231200169","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,24]]}}}