{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:45:03Z","timestamp":1777934703039,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to evaluate the local and systemic side effects of the COVID-19 vaccine in cancer patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>we conducted a cross-sectional study including cancer patients treated at Habib Bourguiba Hospital in Sfax, Tunisia between January and March 2022. Patients should have received at least 1 dose of a COVID-19 vaccine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We interviewed a total of 106 patients, of which 80.2% were actively treated. Mean age was 52.52. Patients were vaccinated by the Pfizer\/BioNTech in 59.8% and the Oxford\/AstraZeneca in 22.5%. The most frequent grade 1 or 2 adverse events occurring within 7 days were: pain at injection site (71.7%) and fatigue (38.7%). Only 2 patients developed grade 3 toxicity following vaccination. The most systemic side effects were fatigue (35.8%), fever (25.4%), headache (16.9%) and arthralgia (15.1%). They were more common after the first dose of Oxford\/AstraZeneca vaccine compared to the Pfizer\/BioNTech vaccine (69.6% vs 42.6%; p\u2009=\u20090.03). Risk of any grade toxicity (local or systemic) following the first dose was correlated with female sex (p\u2009=\u20090.033).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study showed that systemic side effects were more common after the first dose of Oxford\/AstraZeneca vaccine compared to the Pfizer\/BioNTech vaccine in cancer patient, with the predominance of any grade of local or systemic toxicity in women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552241285034","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T15:11:31Z","timestamp":1726585891000},"page":"38-42","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Local and systemic side effects of COVID-19 vaccine in Tunisian cancer patients: A prospective single center study"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4956-9551","authenticated-orcid":false,"given":"Wala","family":"Ben Kridis","sequence":"first","affiliation":[{"name":"Habib Bourguiba Hospital University of Sfax"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olfa","family":"Boudawara","sequence":"additional","affiliation":[{"name":"Habib Bourguiba Hospital University of Sfax"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afef","family":"Khanfir","sequence":"additional","affiliation":[{"name":"Habib Bourguiba Hospital University of Sfax"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,9,17]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Venkatesulu B Chandrasekar V Girdhar P et al. A systematic review and meta-analysis of cancer patients affected by a novel coronavirus. medRxiv. 29 mai 2020;2020.05.27.20115303."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30442-3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.05.062"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1200\/GO.20.00444"},{"key":"e_1_3_3_6_2","article-title":"High mortality among patients with cancer and COVID-19 infection: the experience of a Brazilian cancer center","volume":"19","author":"Barros LdR","year":"2021","unstructured":"Barros LdR, Magalh\u00e3es Filho MAF, Alves RdB, et al. High mortality among patients with cancer and COVID-19 infection: the experience of a Brazilian cancer center. Einstein Sao Paulo Braz 2021; 19: eAO6254.","journal-title":"Einstein Sao Paulo Braz"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32466-1"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-022-07040-3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13143573"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028561"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(21)00224-3"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-023-09357-5"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552241285034","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10781552241285034","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552241285034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:30:22Z","timestamp":1777689022000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10781552241285034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,17]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/10781552241285034"],"URL":"https:\/\/doi.org\/10.1177\/10781552241285034","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,17]]}}}