{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T19:17:22Z","timestamp":1788463042713,"version":"build-2803163510"},"reference-count":36,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To gather nurses\u2019 perceptions nursing hematologic management on patients undergoing CAR-T cell therapy. A combined approach using statistical analysis and Large Language Model for open-ended questionnaire processing (LLMs) was adopted to analyze and interpret open-ended questionnaire responses, focusing on the critical issues in managing patients\u2019 post-CAR T-cell therapy infusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Observational questionnaire-based survey study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed data through descriptive statistical methods and used generative artificial intelligence to summarize four open-ended answers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 89 Italian oncology nurses participated in the present study. The semiautomatic analysis of the open-ended responses, using a procedure based on a freely available large language model, allowed us to identify and summarize the main concerns expressed by the professionals regarding the critical issues in managing post-CAR T-cell infusion patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Addressing the highlighted issues through targeted improvements in staffing, training, and resource allocation could significantly enhance patient outcomes and care quality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552261482046","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:19:23Z","timestamp":1788275963000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["CAR-T cell therapy in advanced practice nursing management. A Statistical and Large Language Model approach to highlight critical issues"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9738-3479","authenticated-orcid":false,"given":"Elsa","family":"Vitale","sequence":"first","affiliation":[{"name":"Healthcare Directions, ASL Bari, Bari, Italy"},{"name":"Scientific Directorate, IRCCS Istituto Tumori \u201cGiovanni Paolo II\u201d, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luana","family":"Conte","sequence":"additional","affiliation":[{"name":"University of Salento"},{"name":"University of Salento and Local Health Authority of Lecce"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana","family":"Nepoti","sequence":"additional","affiliation":[{"name":"IRCCS Sant'Orsola Azienda Ospedaliera Universitaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Munaretto","sequence":"additional","affiliation":[{"name":"Direzione Servizio Infermieristico Tecnico Riabilitativo, IRCCS Istituto Auxologico Italiano"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"De Nunzio","sequence":"additional","affiliation":[{"name":"University of Salento and Local Health Authority of Lecce"},{"name":"University of Salento"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Vaccaro","sequence":"additional","affiliation":[{"name":"Ematologia, IRCCS Policlinico Universitario Fondazione Agostino Gemelli"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-023-00754-1"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00933-8"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2213614"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-022-00629-1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.620312"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/OP.22.00315"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.soncn.2023.151478"},{"key":"e_1_3_3_9_2","first-page":"27","article-title":"Management across settings: an ambulatory and community perspective for patients undergoing CAR T-cell therapy in multiple care settings","volume":"23","author":"Beaupierre A","year":"2019","unstructured":"Beaupierre A, Lundberg R, Marrero L, et al. 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