{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T18:40:38Z","timestamp":1792348838558,"version":"4.4.0"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Oncol Pharm Pract"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Medication safety is an underdeveloped dimension of pediatric oncology survivorship despite persistent medication exposure after cancer therapy. This review synthesizes evidence on chronic medication burden and polypharmacy, high-risk medications, drug interactions, adherence and medication reconciliation, caregiver and survivor education, household medication safety, and systems-level strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A focused narrative review was conducted using targeted searches of PubMed-indexed literature and iterative reference-list and citation review through August 2026. Priority was given to survivor-specific cohort studies, systematic reviews, and current survivorship guidance. When direct survivorship evidence was limited, selected broader literature on multimorbidity, drug-supplement interactions, and pediatric-to-adult transition was included to inform potentially transferable medication-safety mechanisms and care processes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Summary<\/jats:title>\n                    <jats:p>Survivor-specific evidence demonstrates persistent medication use, polypharmacy in selected high-risk groups, increased early post-therapy opioid prescribing and claims-based indicators of potential opioid misuse, greater psychoactive medication use than in sibling controls, complementary medicine use with potential drug interactions, and cost-related nonadherence. Broader multimorbidity and transition literature informs comprehensive interaction review, medication reconciliation, and structured transfer of medication-management responsibility, while pediatric oncology studies identify home medication errors, caregiver medication-management challenges, and potential roles for pharmacists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Medication safety should be approached as a longitudinal, exposure-aware component of survivorship care that balances treatment of late effects with prevention of medication-related harm. Major evidence gaps include survivor-specific data on adverse drug events, clinically consequential interactions, potentially inappropriate prescribing, deprescribing, pharmacist-led interventions, and medication safety during transition to adult care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10781552261498054","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:38:57Z","timestamp":1792071537000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Medication safety in pediatric oncology survivorship: Polypharmacy, high-risk medications, drug interactions, adherence, and caregiver education"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4776-0918","authenticated-orcid":false,"given":"Ayodeji","family":"Otufowora","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, NewYork-Presbyterian Hospital, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3664-3986","authenticated-orcid":false,"given":"Adedoyin","family":"Okusanya","sequence":"additional","affiliation":[{"name":"First Health Consultants LLC, Tampa, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7561-4707","authenticated-orcid":false,"given":"Aderonke","family":"Okusanya","sequence":"additional","affiliation":[{"name":"Western New England University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2024.6812"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-023-00802-w"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-053127"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.11.063"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.642544"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkac059"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-021-01161-0"},{"key":"e_1_3_2_9_2","first-page":"4521","article-title":"Opioid use and misuse in children, adolescents, and young adults with cancer: a systematic review of the literature","volume":"29","author":"Beauchemin M","year":"2021","unstructured":"Beauchemin M, Dorritie R, Hershman DL. Opioid use and misuse in children, adolescents, and young adults with cancer: a systematic review of the literature. Support Care Cancer 2021; 29: 4521\u20134527.","journal-title":"Support Care Cancer"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-021-01051-5"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-2434"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000447700"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/10781552221079786"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/27527530241300056"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33289"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000492"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djac049"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2022.3744"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr7103a1"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkaa057"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-012-0250-x"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210701"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2019.01.028"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2018-2587"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.3233\/PRM-200705"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30648"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/jep.13737"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcsop.2023.100373"},{"key":"e_1_3_2_29_2","first-page":"1656","article-title":"Improving pharmacist-led pediatric patient education on oral chemotherapy at home","volume":"10","author":"Patel A","year":"2023","unstructured":"Patel A, Nguyen CM, Willins K, et al. Improving pharmacist-led pediatric patient education on oral chemotherapy at home. Children (Basel) 2023; 10: 1656.","journal-title":"Children (Basel)"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2019.09.018"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2023.230227R1"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1177\/10781552211068139"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedn.2020.01.002"},{"key":"e_1_3_2_34_2","article-title":"Transitional care interventions and patient empowerment in adolescents and young adults with chronic conditions: a scoping review for medication management","volume":"22","author":"Jamari J","year":"2026","unstructured":"Jamari J, Hatah E, Mohamed Shah N. Transitional care interventions and patient empowerment in adolescents and young adults with chronic conditions: a scoping review for medication management. Res Social Adm Pharm 2026; 22. Epub ahead of print 14 August 2026.\u00a0DOI: https:\/\/doi.org\/10.1016\/j.sapharm.2026.08.003","journal-title":"Res Social Adm Pharm"}],"container-title":["Journal of Oncology Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552261498054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10781552261498054","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10781552261498054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T17:48:01Z","timestamp":1792345681000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10781552261498054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":33,"alternative-id":["10.1177\/10781552261498054"],"URL":"https:\/\/doi.org\/10.1177\/10781552261498054","relation":{},"ISSN":["1078-1552","1477-092X"],"issn-type":[{"value":"1078-1552","type":"print"},{"value":"1477-092X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]},"article-number":"10781552261498054"}}