{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:45:26Z","timestamp":1777934726287,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Wilderness &amp; Environmental Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Heat stroke represents a growing public health concern, exacerbated by rising temperatures and prolonged heat waves. This study examines the clinical profile, prognostic markers, and outcomes of heat stroke patients presenting to a tertiary care center in India and compares findings with previous global studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the clinical profile, prognostic markers, and outcomes of heat stroke patients presenting to a tertiary care center in India and to compare findings with previous global studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted between March to July 2024. Data on demographics, clinical parameters, laboratory values, and outcomes were collected and analyzed. Primary outcomes were mortality and functional recovery. Statistical tests included chi-square, Mann-Whitney U test, and multivariate logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 43 patients, the mean age was 57 years, and 67% were male. The overall mortality rate was 21%. Significant predictors of mortality included hypotension (SBP &lt;100 mm\u2009Hg,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.040), tachypnea (RR &gt;20\/min,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001), Glasgow Coma Scale score &lt;9 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), elevated creatinine, and multi-organ dysfunction syndrome (MODS) involving renal and CNS systems (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Middle-aged, active individuals were disproportionately affected due to occupational exposure to high ambient temperatures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings highlight key clinical and biochemical predictors of poor outcomes in heat stroke. Indian patients who are middle-aged individuals, possibly exposed due to outdoor occupations, may face greater exposure to high ambient temperatures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10806032251361709","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T05:57:00Z","timestamp":1755669420000},"page":"12-16","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Profile and Outcome of Heat-Stroke Patients Presenting to the Emergency Department of a Tertiary Care Center in Eastern Part of India"],"prefix":"10.1177","volume":"37","author":[{"given":"Divendu","family":"Bhushan","sequence":"first","affiliation":[{"name":"All India Institute of Medical Sciences Patna"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muskan","family":"Dogney","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences Patna"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8334-3636","authenticated-orcid":false,"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences Patna"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Iqbal","family":"A. N.","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences Patna"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Vaibhaw","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences Patna"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8,19]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"Heat and Health [Internet]","author":"World Health Organization","year":"2023","unstructured":"World Health Organization. Heat and Health [Internet]. WHO; 2023. https:\/\/www.who.int\/."},{"key":"e_1_3_2_3_2","volume-title":"Climate and Health Profile for India: Heat Wave Impact Assessment","author":"National Health Mission, Ministry of Health and Family Welfare, Government of India","year":"2024","unstructured":"National Health Mission, Ministry of Health and Family Welfare, Government of India. Climate and Health Profile for India: Heat Wave Impact Assessment. Ministry of Health and Family Welfare; 2024."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000206469.33615.02"},{"issue":"9","key":"e_1_3_2_5_2","first-page":"877","article-title":"Prognostic factors in heat stroke","volume":"120","author":"Argaud L","year":"2007","unstructured":"Argaud L, Ferry T, Le QH, et al. Prognostic factors in heat stroke. Am J Med. 2007;120(9):877-84.","journal-title":"Am J Med"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197032"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10028-1685"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-129-3-199808010-00001"},{"issue":"10","key":"e_1_3_2_9_2","first-page":"591","article-title":"Clinical profile and outcome of heat-related illnesses","volume":"19","author":"Kalaiselvan MS","year":"2015","unstructured":"Kalaiselvan MS, Renuka MK, Arunkumar AS. Clinical profile and outcome of heat-related illnesses. Indian J Crit Care Med. 2015;19(10):591-97. doi:https:\/\/doi.org\/10.4103\/0972-5229.167048","journal-title":"Indian J Crit Care Med"},{"issue":"11","key":"e_1_3_2_10_2","first-page":"1467","article-title":"Cooling methods in heat stroke","volume":"289","author":"Bouchama A","year":"2007","unstructured":"Bouchama A, Dehbi M, Chaves-Carballo E. Cooling methods in heat stroke. JAMA. 2007;289(11):1467-70.","journal-title":"JAMA"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00301.2010"},{"issue":"7","key":"e_1_3_2_12_2","first-page":"8034","article-title":"Limitations to thermoregulation and acclimatization in high heat environments","volume":"12","author":"Hanna EG","year":"2015","unstructured":"Hanna EG, Tait PW. Limitations to thermoregulation and acclimatization in high heat environments. Glob Health Action. 2015 Jul 15;12(7):8034-74.","journal-title":"Glob Health Action"},{"issue":"8","key":"e_1_3_2_13_2","article-title":"Heat-related illness-Clinical profile and predictors of outcome from a healthcare center in South India","volume":"9","author":"Ninan GA","unstructured":"Ninan GA, Gunasekaran K, Jayakaran JAJ, et al. Heat-related illness-Clinical profile and predictors of outcome from a healthcare center in South India. J Family Med Prim Care. 2020 Aug 25;9(8):4210\u201315. doi:https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_690_20. PMID: 33110834; PMCID: PMC7586615.","journal-title":"J Family Med Prim Care"}],"container-title":["Wilderness &amp; Environmental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10806032251361709","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10806032251361709","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10806032251361709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:32:55Z","timestamp":1777689175000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10806032251361709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,19]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/10806032251361709"],"URL":"https:\/\/doi.org\/10.1177\/10806032251361709","relation":{},"ISSN":["1080-6032","1545-1534"],"issn-type":[{"value":"1080-6032","type":"print"},{"value":"1545-1534","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,19]]}}}