{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:58:52Z","timestamp":1793213932285,"version":"4.5.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T00:00:00Z","timestamp":1721779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>Non-Hodgkin lymphoma (NHL) is one of the most common hematological cancers in the United States. The mortality rate of NHL in the United States is the sixth highest among all cancers. Our cross-sectional study aims to examine the trends and disparity in NHL mortality. We analyzed death certificate data from the Centers for Disease Control and Prevention\u2019s Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) United States to determine the NHL mortality trends among the U.S. population aged \u226515\u2009years. NHL (ICD-10 C82-85) was listed as the underlying cause of death. Age-adjusted mortality rates (AAMRs) per 100,000 individuals and joinpoint trend analysis were performed to determine the average annual percent change (AAPC) in AAMR trends. From 1999 to 2020, NHL accounted for 457,143 deaths in the United States, of which 54% are men and 46% are women. The NHL AAMR decreased significantly from 10.59 to 6.21\u2009per 100,000 individuals with an AAPC of \u22122.55. Men had a higher AAMR than women (10.10 vs 6.29\u2009per 100,000 individuals). Whites recorded the highest AAMR (8.43\u2009per 100,000 individuals), followed by Hispanics (6.32\u2009per 100,000 individuals), Blacks (5.71\u2009per 100,000 individuals), American Indians (5.31\u2009per 100,000 individuals), and Asians (5.10\u2009per 100,000 individuals). Those who lived in the Midwest and the rural areas had the highest AAMR at 8.60 and 8.35\u2009per 100,000 individuals respectively. Despite the declining NHL mortality rate, this study calls for targeted intervention to improve outcomes for susceptible individuals affected by NHL.<\/jats:p>","DOI":"10.1177\/10815589241262003","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T08:14:15Z","timestamp":1718266455000},"page":"723-729","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Non-Hodgkin lymphoma mortality disparities across different sexes, races, and geographic locations"],"prefix":"10.1177","volume":"72","author":[{"given":"Jia Yi","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, New York Medical College at Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Hao","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine\/Pediatrics, Corewell Health, Royal Oak, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aharnish","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, New York Medical College at Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kok Hoe","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Internal Medicine, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Muhsin","family":"Chisti","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E","family":"Ezekwudo","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,7,24]]},"reference":[{"issue":"1","key":"bibr1-10815589241262003","first-page":"5","volume":"9","author":"Thandra KC","year":"2021","journal-title":"Med Sci (Basel)"},{"key":"bibr2-10815589241262003","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1059914"},{"key":"bibr3-10815589241262003","first-page":"1","volume":"42","author":"Ngu H","year":"2022","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"bibr4-10815589241262003","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(20)30031-4"},{"key":"bibr5-10815589241262003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2115304"},{"key":"bibr6-10815589241262003","doi-asserted-by":"publisher","DOI":"10.1016\/j.currproblcancer.2021.100826"},{"key":"bibr7-10815589241262003","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.909008"},{"key":"bibr8-10815589241262003","unstructured":"Cause of Death. International Classification of Diseases (ICD), https:\/\/www.who.int\/standards\/classifications\/classification-of-diseases\/cause-of-death (2023, accessed 8 November 2023)."},{"key":"bibr9-10815589241262003","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13345"},{"key":"bibr10-10815589241262003","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2018.2093"},{"key":"bibr11-10815589241262003","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-022-05785-4"},{"key":"bibr12-10815589241262003","unstructured":"Non-Hodgkin Lymphoma [web site]. 2023. 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