{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:34:59Z","timestamp":1793111699661,"version":"4.5.0"},"reference-count":44,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Hainan Provincial Health Science and Technology Innovation Joint Project","award":["WSJK2024QN043"],"award-info":[{"award-number":["WSJK2024QN043"]}]},{"name":"Zhejiang Provincial Medical and Health Technology Project","award":["2025KY1045"],"award-info":[{"award-number":["2025KY1045"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine"],"abstract":"<jats:sec>\n                    <jats:title>Background and aims:<\/jats:title>\n                    <jats:p>Transcutaneous electrical acupoint stimulation (TEAS) promotes postoperative gastrointestinal recovery. However, existing protocols lack standardization due to unaddressed methodological collinearity between frequency and waveform in previous analyses. We aimed to evaluate the efficacy of TEAS following abdominal surgery and examine whether treatment effects varied across stimulation parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We searched four major databases from inception to April 2026 for randomized controlled trials (RCTs) comparing TEAS with sham\/standard care. Frequency and waveform were systematically reconstructed into a composite \u201cStimulation Pattern\u201d (Intermittent\/Fixed vs Dilatational\/Alternating). Data were pooled using a random-effects model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Twenty RCTs comprising 2615 patients were included. TEAS significantly accelerated the time to first flatus (mean difference (MD)\u2009=\u2009\u22129.08 h,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) and first defecation (MD\u2009=\u2009\u221216.48 h,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), and reduced the incidence of strictly defined postoperative ileus (3 trials; risk ratio\u2009=\u20090.78, 95% confidence interval 0.64\u20130.96;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0214). TEAS also shortened hospital stay and mitigated postoperative nausea, vomiting, and pain. The intermittent\/fixed stimulation pattern was associated with a greater reduction in time to first flatus than the dilatational\/alternating pattern (interaction\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0008). Adverse events were minimal (0%\u20131.8%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>TEAS safely accelerates gastrointestinal motility recovery. While an optimal protocol remains to be established, the intermittent\/fixed stimulation pattern appears to be a promising candidate configuration. Longer or more frequent treatment did not show clear additional benefit, supporting evaluation of a 30-min once-daily regimen as a pragmatic, resource-efficient strategy in future prospective trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10815589261497363","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T04:36:52Z","timestamp":1791434212000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcutaneous electrical acupoint stimulation for postoperative gastrointestinal recovery: A systematic review and meta-analysis using a composite stimulation-pattern framework"],"prefix":"10.1177","author":[{"given":"Bo","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Sichuan Taikang Hospital, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodie","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sichuan Taikang Hospital, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Affiliated Hangzhou First People\u2019s Hospital, School of Medicine, Westlake University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiande D. 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