{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:55:58Z","timestamp":1777643758908,"version":"3.51.4"},"reference-count":51,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T00:00:00Z","timestamp":1569110400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eday Competitividad","doi-asserted-by":"publisher","award":["AGL2013-48993-C2-2-R and AGL2017-86840-C2-2-R"],"award-info":[{"award-number":["AGL2013-48993-C2-2-R and AGL2017-86840-C2-2-R"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"name":"EUH2020 program for provide the MSCA-IF","award":["CAPSALIPHARM Grant Agreement-748314"],"award-info":[{"award-number":["CAPSALIPHARM Grant Agreement-748314"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Food sci. technol. int."],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>\n                    Resistant bacteria to antimicrobials are increasingly emerging in medical, food industry and livestock environments. The present research work assesses the capability of Salmonella enterica var Typhimurium to become adapted under the exposure to a natural cauliflower antimicrobial by-product infusion in consecutive repeated exposure cycles. Caenorhabditis elegans was proposed as in vivo host-test organism to compare possible changes in the virulent pattern of the different rounds treated S. enterica var Typhimurium and untreated bacterial cells. According to the obtained results, S. enterica var Typhimurium was able to generate resistance against a repeated exposure to cauliflower by-product infusion 5% (w\/v), increasing the resistance with the number of exposed repetitions. Meanwhile, at the first exposure, cauliflower by-product infusion was effective in reducing S. enterica var Typhimurium (\u22481 log\n                    <jats:sub>10<\/jats:sub>\n                    cycle), and S. enterica var Typhimurium became resistant to this natural antimicrobial after the second and third treatment-round and was able to grow (\u22481 log\n                    <jats:sub>10<\/jats:sub>\n                    cycle). In spite of the increased resistance observed for repeatedly treated bacteria, the present study reveals no changes on C. elegans infection effects between resistant and untreated S. enterica var Typhimurium, according to phenotypic parameters evaluation (lifespan duration and egg-laying).\n                  <\/jats:p>","DOI":"10.1177\/1082013219873500","type":"journal-article","created":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T01:45:05Z","timestamp":1569203105000},"page":"151-159","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Occurrence of\n                    <i>Salmonella typhimurium<\/i>\n                    resistance under sublethal\/repeated exposure to cauliflower infusion and infection effects on\n                    <i>Caernohabditis elegans<\/i>\n                    host test organism"],"prefix":"10.1177","volume":"26","author":[{"given":"Maria","family":"Sanz-Puig","sequence":"first","affiliation":[{"name":"Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos \u2013 Consejo Superior de Investigaciones Cient\u00edficas (IATA-CSIC), Val\u00e8ncia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Arana-Lozano","sequence":"additional","affiliation":[{"name":"Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos \u2013 Consejo Superior de Investigaciones Cient\u00edficas (IATA-CSIC), Val\u00e8ncia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M Consuelo","family":"Pina-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Institute of Life Technologies, HES.SO VALAIS-WALLIS, Sion, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Unidad Asociada al CSIC, Universidad Polit\u00e9cnica de Cartagena, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2323-8463","authenticated-orcid":false,"given":"Antonio","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos \u2013 Consejo Superior de Investigaciones Cient\u00edficas (IATA-CSIC), Val\u00e8ncia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dolores","family":"Rodrigo","sequence":"additional","affiliation":[{"name":"Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos \u2013 Consejo Superior de Investigaciones Cient\u00edficas (IATA-CSIC), Val\u00e8ncia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,9,22]]},"reference":[{"key":"bibr1-1082013219873500","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00830-7"},{"key":"bibr2a-1082013219873500","doi-asserted-by":"crossref","unstructured":"Ahmed AH, Fatma IE, Saleh MS, Mahmoud AA, and Gamilat AE. 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Characterization of Virulence-Associated Genes, Antimicrobial Resistance Genes, and Class 1 Integrons in Salmonella enterica serovar Typhimurium Isolates from Chicken Meat and Humans in Egypt.\n                      Foodborne Pathogens and Disease\n                      13: 281\u2013289.","DOI":"10.1089\/fpd.2015.2097"},{"key":"bibr2-1082013219873500","doi-asserted-by":"publisher","DOI":"10.4155\/fsoa-2017-0109"},{"key":"bibr3-1082013219873500","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2014.06.054"},{"key":"bibr4-1082013219873500","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2017.07.022"},{"key":"bibr5-1082013219873500","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12152"},{"key":"bibr6-1082013219873500","doi-asserted-by":"publisher","DOI":"10.4081\/ijfs.2018.7223"},{"key":"bibr7-1082013219873500","doi-asserted-by":"publisher","DOI":"10.1177\/1753425916679255"},{"key":"bibr8-1082013219873500","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-69.9.2274"},{"key":"bibr9-1082013219873500","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2014.10.027"},{"key":"bibr10-1082013219873500","first-page":"544","volume":"12","author":"Christopher LP","year":"2013","journal-title":"Caenorhabditis elegans. 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