{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:13:29Z","timestamp":1783642409575,"version":"3.55.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Guangdong Medical Science and Technology Research Fund Project","award":["A2022336"],"award-info":[{"award-number":["A2022336"]}]},{"name":"Zhongshan social welfare science and technology research project","award":["2022B1101"],"award-info":[{"award-number":["2022B1101"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Biotherapy and Radiopharmaceuticals"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Background:<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>In this single-center retrospective study, the authors evaluated whether real-time ultrasound-guided positioning of an implantable venous access port catheter tip at the superior vena cava-right atrial junction (SVC-RAJ) reduces the risk of catheter-related thrombosis (CRT) in adult patients with cancer and developed a multivariable risk prediction model to support individualized prevention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Clinical data from 600 consecutive patients who underwent port implantation at Zhongshan People\u2019s Hospital were analyzed. Patients were grouped according to final catheter tip position (SVC-RAJ versus non-SVC-RAJ), and CRT incidence was compared between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>\n                      The overall incidence of CRT was 30.33% (182\/600) and was significantly lower in the SVC-RAJ group than in the non-SVC-RAJ group (22.42% vs. 38.73%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). In multivariable analysis, catheter tip positioning at the SVC-RAJ remained an independent protective factor (odds ratio = 0.517, 95% confidence interval [CI]: 0.353\u20130.756). Age, body mass index (BMI), tumor stage, neutrophil-to-lymphocyte ratio, D-dimer level, catheterization duration, and prophylactic anticoagulation status were also independently associated with CRT. A nomogram integrating these variables demonstrated good discrimination (area under the curve = 0.866, 95% CI: 0.837\u20130.895), with a sensitivity of 70.33% and a specificity of 85.89%. Performance across specific age or BMI strata was not separately evaluated in this study, and further stratified validation in larger datasets is needed to assess model consistency across demographic subgroups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>These findings support ultrasound-guided SVC-RAJ positioning as a clinically relevant strategy for reducing CRT risk and maintaining reliable venous access in contemporary oncology care pathways.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10849785261442223","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T09:22:15Z","timestamp":1777886535000},"page":"459-468","source":"Crossref","is-referenced-by-count":0,"title":["Radiopharmaceutical Oncology Care Supported by Ultrasound-Guided Superior Vena Cava-Right Atrial Junction Port Tip Positioning in Adult Cancer Patients"],"prefix":"10.1177","volume":"41","author":[{"given":"Quan","family":"Ling","sequence":"first","affiliation":[{"name":"Zhongshan City People\u2019s Hospital, Zhongshan City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinqi","family":"Yang","sequence":"additional","affiliation":[{"name":"Zhongshan City People\u2019s Hospital, Zhongshan City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junlin","family":"Wen","sequence":"additional","affiliation":[{"name":"Zhongshan City People\u2019s Hospital, Zhongshan City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhongshan City People\u2019s Hospital, Zhongshan City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7123-8044","authenticated-orcid":false,"given":"Yong","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhongshan City People\u2019s Hospital, Zhongshan City, Guangdong Province, 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