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Method: ADHD adults ( n = 39) and healthy controls ( n = 18) underwent a nocturnal polysomnography (PSG) followed by a Maintenance of Wakefulness Test (MWT), a simulated driving task, and a neuropsychological evaluation. Results: ADHD patients had shorter mean sleep latency on the MWT and worse driving performance than controls. They also made more errors on attention and executive functioning tests. Logistic regression analyses showed that inhibition deficits and objective daytime sleepiness predicted highway driving performance in ADHD. Conclusion: Our study shows that not only inhibitory control deficits but also pathological level of alertness independently contribute to highway driving impairment in ADHD patients, providing a better understanding of the pathophysiological mechanisms involved in ADHD.<\/jats:p>","DOI":"10.1177\/1087054716633751","type":"journal-article","created":{"date-parts":[[2016,3,23]],"date-time":"2016-03-23T21:50:57Z","timestamp":1458769857000},"page":"1475-1486","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Objective Level of Alertness and Inhibitory Control Predict Highway Driving Impairment in Adults With ADHD"],"prefix":"10.1177","volume":"24","author":[{"given":"St\u00e9phanie","family":"Bioulac","sequence":"first","affiliation":[{"name":"P\u00f4le Universitaire Psychiatrie Enfants et Adolescents, Bordeaux, France"},{"name":"Universit\u00e9 de Bordeaux, France"},{"name":"Unit\u00e9 de Service et de 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