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Method: Resting-state functional connectivity (RSFC) of amygdala subregions and their correlations with EL scores were evaluated in 35 drug-na\u00efve boys with ADHD and 30 age-matched healthy controls (HC). Results: Compared with HC, altered RSFC were detected differently for each amygdala subregion in ADHD: altered RSFC of BLA with the thalamus and vermis; aberrant RSFC of CMA with the superior temporal gyrus\/pole and insula, precuneus and cerebellum; reduced RSFC of SFA with dorsal frontoparietal cortices. Within ADHD, higher EL scores were associated with reduced negative RSFC of SFA with the dorsolateral prefrontal cortex and inferior parietal lobe. Conclusion: Diffuse alterations of amygdala subregion-based networks are associated with ADHD, and the weaker SFA\u2013frontoparietal networks might be involved in the hypothesized top\u2013down effortful regulation of emotion.<\/jats:p>","DOI":"10.1177\/1087054716661419","type":"journal-article","created":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T21:43:25Z","timestamp":1470692605000},"page":"1661-1673","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":34,"title":["Integrity of Amygdala Subregion-Based Functional Networks and Emotional Lability in Drug-Na\u00efve Boys With ADHD"],"prefix":"10.1177","volume":"24","author":[{"given":"Xiaoyan","family":"Yu","sequence":"first","affiliation":[{"name":"Peking University Sixth Hospital\/Institute of Mental Health, Beijing, China"},{"name":"National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China"},{"name":"Joint first authors"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Liu","sequence":"additional","affiliation":[{"name":"Peking University Sixth Hospital\/Institute of Mental Health, Beijing, China"},{"name":"National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China"},{"name":"Joint first authors"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai","family":"Chen","sequence":"additional","affiliation":[{"name":"Centre & Discipline of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy; 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