{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T21:10:34Z","timestamp":1789938634471,"version":"4.0.1"},"reference-count":68,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2017,5,6]],"date-time":"2017-05-06T00:00:00Z","timestamp":1494028800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Atten Disord"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>\n                    Objective: Children with ADHD show substantial deficits in social cognitive abilities. Oxytocin, mediated through its specific receptor (OXTR), is involved in the regulation of social behavior and social cognition. Method: The entire coding sequence of the human OXT and OXTR genes were sequenced to identify mutations and single nucleotide polymorphisms (SNPs) in 151 children with ADHD (ADHD-combined, n = 51; inattentive subtype, n = 50; ADHD-C plus conduct disorder [CD], n = 50; 11-18 years) and 100 healthy controls. Results: We examined the association of three detected SNPs of OXTR with social cognition deficits. A significant association was shown between the children with ADHD and children with CT\/TT genotypes of rs4686302 (\u03c7\n                    <jats:sup>2<\/jats:sup>\n                    = 3.695; p = .037). ADHD children with CT\/TT genotype for the OXTR rs4686302 performed significantly lower on the facial emotion recognition task than those with CC genotype. Conclusion: OXTR rs4686302 polymorphism was shown to be a genetic marker in social cognition deficits in ADHD children.\n                  <\/jats:p>","DOI":"10.1177\/1087054717706757","type":"journal-article","created":{"date-parts":[[2017,5,6]],"date-time":"2017-05-06T07:32:09Z","timestamp":1494055929000},"page":"702-711","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Variation in the Oxytocin Receptor Gene Is Associated With Social Cognition and ADHD"],"prefix":"10.1177","volume":"23","author":[{"given":"Tu\u011fba","family":"Kalyoncu","sequence":"first","affiliation":[{"name":"Tepecik Teaching and Research Hospital, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burcu","family":"\u00d6zbaran","sequence":"additional","affiliation":[{"name":"Ege University, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sezen","family":"K\u00f6se","sequence":"additional","affiliation":[{"name":"Ege University, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcseyin","family":"Onay","sequence":"additional","affiliation":[{"name":"Ege University, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,5,6]]},"reference":[{"key":"bibr1-1087054717706757","volume-title":"Manual for the Child Behavior Checklist\/4-18 and 1991 profile","author":"Achenbach T. 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