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The present study utilized data from the Multimodal Treatment Study of ADHD to examine potential mechanisms that may account for the association between childhood ADHD and becoming pregnant or causing a pregnancy by age 18. Method: Participants were 579 children with ADHD and 289 comparison peers followed over 16 years. Results: Relative to the comparison group, those with childhood ADHD were at more than two times increased risk of early pregnancy. Univariately, persistence of ADHD symptoms, delinquency\/substance use, and academic performance\/achievement during adolescence each mediated the association between childhood ADHD and early pregnancy. When considered together, only delinquency\/substance use remained a significant mediator of this relationship. Conclusion: Findings point toward specific targets of intervention for youth with ADHD to prevent early pregnancy.<\/jats:p>","DOI":"10.1177\/1087054717730610","type":"journal-article","created":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T02:09:36Z","timestamp":1506132576000},"page":"1955-1965","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":33,"title":["Childhood ADHD and Involvement in Early Pregnancy: Mechanisms of Risk"],"prefix":"10.1177","volume":"24","author":[{"given":"Michael C.","family":"Meinzer","sequence":"first","affiliation":[{"name":"University of Maryland, College Park, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn A.","family":"LeMoine","sequence":"additional","affiliation":[{"name":"University of Maryland, College Park, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea L.","family":"Howard","sequence":"additional","affiliation":[{"name":"Carleton University, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamarie","family":"Stehli","sequence":"additional","affiliation":[{"name":"University of California, Irvine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. 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