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Method: Drug-free adult patients with ADHD ( n = 100) or hypersomnia ( n = 100) were evaluated using a structured clinical interview and self-report questionnaires on ADHD symptoms and EDS. Results: In all, 61% of patients with hypersomnia had clinically significant ADHD symptoms with 25% having an ADHD diagnosis (with both childhood and adulthood ADHD symptoms) and 36% ADHD-like symptoms, without history of childhood ADHD. EDS was reported in 47% of patients with ADHD, among whom 22% had a hypersomnolence disorder. Conclusion: We confirmed the high frequency of ADHD and ADHD-like symptoms in central hypersomnia, and of EDS and hypersomnolence in ADHD in adults. The nature of the link between EDS, inattention, and hyperactivity appears to be complex that may involve either a cause\u2013effect relationship or intrinsic features of a similar neurodevelopmental dysfunction.<\/jats:p>","DOI":"10.1177\/1087054718775826","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T09:57:23Z","timestamp":1526551043000},"page":"555-564","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["Association of Inattention, Hyperactivity, and Hypersomnolence in Two Clinic-Based Adult Cohorts"],"prefix":"10.1177","volume":"24","author":[{"given":"R\u00e9gis","family":"Lopez","sequence":"first","affiliation":[{"name":"Centre National de R\u00e9f\u00e9rence Narcolepsie Hypersomnies, Unit\u00e9 des Troubles du Sommeil, Service de Neurologie, H\u00f4pital Gui de Chauliac, Montpellier, France"},{"name":"Inserm U1061, Montpellier, France"},{"name":"Universit\u00e9 de Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Arthur","family":"Micoulaud-Franchi","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Sommeil, H\u00f4pital Pellegrin, Bordeaux, France"},{"name":"Universit\u00e9 de Bordeaux, France"},{"name":"CNRS, SANPSY, USR 3413, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Camodeca","sequence":"additional","affiliation":[{"name":"Centre National de R\u00e9f\u00e9rence Narcolepsie Hypersomnies, Unit\u00e9 des Troubles du Sommeil, Service de Neurologie, H\u00f4pital Gui de Chauliac, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Gachet","sequence":"additional","affiliation":[{"name":"Department of Emergency Psychiatry and Post Acute Care, H\u00f4pital Lapeyronie, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Jaussent","sequence":"additional","affiliation":[{"name":"Inserm U1061, Montpellier, France"},{"name":"Universit\u00e9 de Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Dauvilliers","sequence":"additional","affiliation":[{"name":"Centre National de R\u00e9f\u00e9rence Narcolepsie Hypersomnies, Unit\u00e9 des Troubles du Sommeil, Service de Neurologie, H\u00f4pital Gui de Chauliac, Montpellier, France"},{"name":"Inserm U1061, Montpellier, France"},{"name":"Universit\u00e9 de Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,5,17]]},"reference":[{"key":"bibr1-1087054718775826","volume-title":"International Classification of Sleep Disorders-Third Edition (ICSD-3)","author":"American Academy of Sleep Medicine","year":"2014"},{"key":"bibr2-1087054718775826","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"bibr3-1087054718775826","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2080"},{"key":"bibr4-1087054718775826","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3756"},{"key":"bibr5-1087054718775826","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.1.99"},{"key":"bibr6-1087054718775826","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033525"},{"key":"bibr7-1087054718775826","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2958"},{"key":"bibr8-1087054718775826","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.08.007"},{"key":"bibr9-1087054718775826","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14m09087"},{"key":"bibr10-1087054718775826","volume-title":"Conners\u2019 Adult ADHD Rating Scales (CAARS)","author":"Conners C. 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