{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T02:02:18Z","timestamp":1786759338356,"version":"build-2736575974"},"reference-count":63,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T00:00:00Z","timestamp":1536883200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Atten Disord"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>Objective: The objective of this study was to assess health-related quality of life (HRQoL) in adult ADHD. Method: U.K. residents aged 18 to 55 years with ADHD and no major mental health comorbidities completed an online survey of disorder history, the EuroQoL 5-Dimensions 5-Level (EQ-5D-5L), and the Work Productivity and Activity Impairment Questionnaire: General Health (WPAI:GH). ADHD Rating Scale-IV (ADHD-RS-IV) score was assessed by telephone. Results: In total, 233 participants completed the study (mean age 32.6 years; 65.2% women). Mean ( SD) ADHD-RS-IV total score, EQ-5D utility, and visual analog scale (VAS) scores were 43.5 (7.88), 0.74 (.21), and 69.8 (17.76), respectively. Mean ( SD) WPAI:GH scores indicated that health problems caused 45.7% (29.9) overall work impairment and 45.8% (28.9) impairment in regular daily activities. Greater work and activity impairment were both significantly independently associated with lower utility after adjusting for age, gender, and somatic comorbidities. Conclusion: Adult ADHD impairs HRQoL, work productivity, and regular daily activities.<\/jats:p>","DOI":"10.1177\/1087054718799367","type":"journal-article","created":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T06:01:30Z","timestamp":1536904890000},"page":"1610-1623","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Health-Related Quality of Life and Work Productivity of Adults With ADHD: A U.K. Web-Based Cross-Sectional Survey"],"prefix":"10.1177","volume":"23","author":[{"given":"Alain","family":"Joseph","sequence":"first","affiliation":[{"name":"Shire, Zug, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte E.","family":"Kosmas","sequence":"additional","affiliation":[{"name":"ICON, Oxfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Patel","sequence":"additional","affiliation":[{"name":"ICON, Oxfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Doll","sequence":"additional","affiliation":[{"name":"ICON, Oxfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Asherson","sequence":"additional","affiliation":[{"name":"King\u2019s College London, Greater London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,9,14]]},"reference":[{"key":"bibr1-1087054718799367","doi-asserted-by":"publisher","DOI":"10.2147\/POR.S64348"},{"key":"bibr2-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-13-253"},{"key":"bibr3-1087054718799367","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994","edition":"4"},{"key":"bibr4-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"bibr5-1087054718799367","doi-asserted-by":"publisher","DOI":"10.2217\/npy.14.16"},{"key":"bibr6-1087054718799367","doi-asserted-by":"publisher","DOI":"10.7243\/2050-0866-3-1"},{"key":"bibr7-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702005652"},{"key":"bibr8-1087054718799367","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n0403"},{"key":"bibr9-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291705006410"},{"key":"bibr10-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-005-8325-z"},{"key":"bibr11-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-10-47"},{"key":"bibr12-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9981-9"},{"key":"bibr13-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2008.01830.x"},{"key":"bibr14-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.114.145185"},{"key":"bibr15-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1007\/s10802-008-9246-4"},{"key":"bibr16-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2009.02008.x"},{"key":"bibr17-1087054718799367","volume-title":"Statistical power analyses for the behavioral sciences","author":"Cohen J.","year":"1988","edition":"2"},{"key":"bibr18-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-009-0046-3"},{"key":"bibr19-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031500"},{"key":"bibr20-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2007.038448"},{"key":"bibr21-1087054718799367","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-013-0502-3"},{"key":"bibr22-1087054718799367","unstructured":"Dolan P., Gudex C., Kind P., Williams A. 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