{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:09:50Z","timestamp":1786115390351,"version":"build-2736575974"},"reference-count":36,"publisher":"SAGE Publications","issue":"6-7","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100010877","name":"ViiV Healthcare","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100010877","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Patient Care and STDs"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:p>We examined pre-exposure prophylaxis (PrEP) persistence and associated characteristics among a nationwide sample of US men who have sex with men (MSM). Sexually active, HIV-negative MSM aged \u226515 years were recruited online through the American Men\u2019s Internet Survey, an annual survey; the current analysis uses cross-sectional data collected between December 2023 and August 2024. Participants reported PrEP use and duration. PrEP persistence was defined as continuous PrEP use for \u226512 months. Poisson regression models estimated associations between sociodemographic and behavioral factors and PrEP persistence. Among 3953 MSM, 40% were currently using PrEP, and 72% of those had maintained use for \u226512 months. Most participants were using daily oral PrEP, while 3.2% reported use of long-acting injectable cabotegravir. In multi-variable analyses, MSM aged 25\u201329 years versus \u226540 years (prevalence ratio [PR]: 0.75, 95% confidence interval [CI], 0.57, 0.98) and those without health insurance versus with private insurance (PR: 0.60, 95% CI, 0.37, 0.96) were less likely to maintain PrEP use. MSM reporting condomless anal sex (PR: 1.41, 95% CI, 1.05, 1.88) and more than one male partner (PR: 2.13, 95% CI, 1.56, 2.92) in the past year were more likely to sustain PrEP use. No associations were observed for race\/ethnicity, region, illicit drug use, or mental health. Most current PrEP users reported sustained use for \u226512 months. Findings should be interpreted in light of limitations, including potential selection bias due to online recruitment. Younger and uninsured MSM had lower persistence, highlighting the need for targeted interventions to promote long-term PrEP engagement and reduce HIV risk.<\/jats:p>","DOI":"10.1177\/10872914261453151","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T06:00:16Z","timestamp":1779861616000},"page":"268-276","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristics Associated with HIV Pre-Exposure Prophylaxis Persistence Among Men Who Have Sex with Men in the United States: Results from the American Men\u2019s Internet Survey, 2023\u20132024"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6041-2320","authenticated-orcid":false,"given":"Duygu","family":"Islek","sequence":"first","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Baral","sequence":"additional","affiliation":[{"name":"Johns Hopkins School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Sarkar","sequence":"additional","affiliation":[{"name":"ViiV Healthcare, Durham, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Acero","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Glick","sequence":"additional","affiliation":[{"name":"Community Health Science &amp; Policy, Health Sciences Center, Louisiana State University, New Orleans, Louisiana, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeb","family":"Jones","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irah","family":"Lucas","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh","family":"Ragone","sequence":"additional","affiliation":[{"name":"ViiV Healthcare, Durham, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariah","family":"Valentine-Graves","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Michael","family":"Smith","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vani","family":"Vannappagari","sequence":"additional","affiliation":[{"name":"ViiV Healthcare, Durham, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"e_1_3_2_2_1","unstructured":"1.HIV Surveillance Report. Diagnoses deaths and prevalence of HIV in the United States and 6 territories and freely associated states 2022. 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