{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T16:25:54Z","timestamp":1793982354025,"version":"4.8.0"},"reference-count":66,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"U.S. Department of Veterans Affairs","award":["RCS 23-081"],"award-info":[{"award-number":["RCS 23-081"]}],"id":[{"id":"https:\/\/ror.org\/05rsv9s98","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Institute of Mental Health","award":["K23MH123335"],"award-info":[{"award-number":["K23MH123335"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Patient Care and STDs"],"published-print":{"date-parts":[[2026,12,1]]},"abstract":"<jats:p>\n                    Little is known about the willingness of parents to support adolescent HIV pre-exposure prophylaxis (PrEP) decision-making and use, and even less is known about the context of sexual health communication (SHC) between adolescents and parents related to PrEP. This study aimed to explore this context and identify parent-related barriers and facilitators to HIV prevention for adolescents at risk for HIV, with a particular focus on PrEP. We conducted individual, in-depth interviews with 14 adolescent sexual minority and gender diverse assigned males and 14 parents of adolescents (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 6 of whom were dyad pairs) recruited from social media and an adolescent medicine clinic in the Northeastern US. Interviews were audio-recorded and transcribed, and transcripts were coded and analyzed using applied thematic analysis to identify themes related to parent-level barriers and facilitators. We identified four main themes: (1) parents\u2019 sex-negative or sex-positive approaches to SHC contributed to specific barriers and facilitators to PrEP; (2) some parents with low willingness to consider PrEP held misconceptions about HIV transmission and PrEP safety; (3) many parents with limited PrEP knowledge were willing to consider PrEP after receiving brief education; and (4) some adolescents would involve their parents in PrEP use to facilitate access. These findings suggest that parental approaches to SHC and PrEP awareness are promising targets for interventions aiming to increase adolescent PrEP uptake. Future studies should explore adolescent-, provider-, and system-level barriers and facilitators to adolescent PrEP uptake, as well as population-level surveys of PrEP willingness in nationally representative samples.\n                  <\/jats:p>","DOI":"10.1177\/10872914261493757","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:36:54Z","timestamp":1790663814000},"page":"492-502","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Parent-Related Barriers and Facilitators to HIV Pre-Exposure Prophylaxis (PrEP) for Adolescent Sexual Minority and Gender Diverse Assigned Males: Parent and Adolescent Perspectives"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1626-2289","authenticated-orcid":false,"given":"Jack C.","family":"Rusley","sequence":"first","affiliation":[{"name":"Division of Adolescent Medicine, Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."},{"name":"Department of Health Services, Policy &amp; Practice, Brown University School of Public Health, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erza","family":"Gashi","sequence":"additional","affiliation":[{"name":"Division of Adolescent Medicine, Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip A.","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease, Department of Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Arrington-Sanders","sequence":"additional","affiliation":[{"name":"Division of Adolescent Medicine, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Psychiatry &amp; Human Behavior, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anashua Rani","family":"Elwy","sequence":"additional","affiliation":[{"name":"Department of Psychiatry &amp; Human Behavior, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."},{"name":"Center for Healthcare Optimization and Implementation Research, VA Bedford Healthcare System, Bedford, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Toma","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease, Department of Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maayan","family":"Leroy-Melamed","sequence":"additional","affiliation":[{"name":"Division of Adolescent Medicine, Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corbin","family":"Gearhart","sequence":"additional","affiliation":[{"name":"Division of Adolescent Medicine, Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeju","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Division of Adolescent Medicine, Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate M.","family":"Guthrie","sequence":"additional","affiliation":[{"name":"Department of Psychiatry &amp; Human Behavior, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"e_1_3_5_2_1","unstructured":"1.US Centers for Disease Control and Prevention (CDC). Press release: HIV Declines Among Young People and Drives Overall Decrease in New HIV Infections. CDC; 2023. Available from: https:\/\/www.cdc.gov\/media\/releases\/2023\/p0523-hiv-declines-among-young-people.html [Last accessed: July8 2024]."},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(19)30037-2"},{"key":"e_1_3_5_4_1","unstructured":"3.US Centers for Disease Control and Prevention (CDC). Estimated HIV Incidence and Prevalence in the United States 2018\u20132022. 29(No.1). HIV Surveillance Supplemental Report; 2024. Available from: https:\/\/www.cdc.gov\/hiv-data\/nhss\/estimated-hiv-incidence-and-prevalence.html [Last accessed: July9 2024]."},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003072"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2023-062599"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2020.0824"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2016.08.006"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-019-02502-y"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-022-03665-x"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/10872914251394786"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/APC.2025.0064"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.2731"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2015.10.250"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1745691614535934"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/S13178-021-00647-X"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-139X(00)00156-7"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.88.10.1542"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/S10560-008-0118-0"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2016.11.002"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1089\/JCHC.24.05.0040"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2019.07.021"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2011.11.006"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/17437199.2016.1240625"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/15546128.2016.1146187"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/15546128.2017.1372829"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/00224499.2016.1267693"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-2066"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-021-03313-w"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/15546128.2023.2233418"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2023.02.015"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1521\/aeap.2023.35.1.85"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2025.09.022"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/1550428X.2014.981627"},{"key":"e_1_3_5_35_1","doi-asserted-by":"crossref","unstructured":"34.Lee N Martin H Patena J et al. Social media recruitment of sexual minority and gender diverse assigned male adolescents to an HIV prevention study. In: Society of Adolescent Health and Medicine (SAHM) Annual Meeting Poster Presentation. 2024.","DOI":"10.1016\/j.jadohealth.2023.11.358"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JBI.2008.08.010"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.3233\/SHTI190841"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.chi.0000166381.68392.02"},{"key":"e_1_3_5_39_1","volume-title":"Applied Thematic Analysis","author":"Guest G","year":"2011","unstructured":"38.Guest G, , MacQueen KM, , Namey EE. Applied Thematic Analysis. Sage; 2011."},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000270"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","unstructured":"40.Rusley JC Arrington-Sanders R Guthrie KM et al. Impact of parent-adolescent relationship quality and sexual health communication on parental willingness to support adolescent use of pre-exposure prophylaxis for HIV: Lessons for post-pandemic sexual health interventions. In: Poster Symposia. 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