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We adapted an evidence-based intervention grounded in social cognitive theory and principles of motivational interviewing originally developed for smoking cessation to also address physical activity and fruit\/vegetable consumption among Latinos exhibiting multiple health risk behaviors. Literature reviews, focus groups, expert consultation, pretesting, and pilot testing were used to inform adaptation decisions. We identified common mechanisms underlying change in smoking, physical activity, and diet used as treatment targets; identified practical models of patient-centered cross-cultural service provision; and identified that family preferences and support as particularly strong concerns among the priority population. Adaptations made to the original intervention are described. The current study is a practical example of how an intervention can be adapted to maximize relevance and acceptability and also maintain the core elements of the original evidence-based intervention. The intervention has significant potential to influence cancer prevention efforts among Latinos in the United States and is being evaluated in a sample of 400 Latino overweight\/obese smokers.<\/jats:p>","DOI":"10.1177\/1090198114560019","type":"journal-article","created":{"date-parts":[[2014,12,20]],"date-time":"2014-12-20T00:55:08Z","timestamp":1419036908000},"page":"65-72","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Adaptation of a Counseling Intervention to Address Multiple Cancer Risk Factors Among Overweight\/Obese Latino Smokers"],"prefix":"10.1177","volume":"42","author":[{"given":"Yessenia","family":"Castro","sequence":"first","affiliation":[{"name":"The University of Texas at Austin, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria E.","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"The University of Texas School of Public Health, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larkin L.","family":"Strong","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana W.","family":"Stewart","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Krasny","sequence":"additional","affiliation":[{"name":"The University of Texas School of Public Health, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eden","family":"Hernandez Robles","sequence":"additional","affiliation":[{"name":"The University of Texas at Austin, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Heredia","sequence":"additional","affiliation":[{"name":"The University of Texas School of Public Health, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire A.","family":"Spears","sequence":"additional","affiliation":[{"name":"Catholic University of America, Washington, DC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virmarie","family":"Correa-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Eakin","sequence":"additional","affiliation":[{"name":"The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Resnicow","sequence":"additional","affiliation":[{"name":"University of Michigan School of Public Health, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Basen-Engquist","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Wetter","sequence":"additional","affiliation":[{"name":"Rice University, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,12,19]]},"reference":[{"key":"bibr1-1090198114560019","doi-asserted-by":"publisher","DOI":"10.1037\/0003-066x.48.1.45"},{"key":"bibr2-1090198114560019","doi-asserted-by":"publisher","DOI":"10.1207\/S15324796ABM2302_3"},{"key":"bibr3-1090198114560019","volume-title":"Planning health promotion programs: An intervention mapping approach","author":"Bartholomew L.","year":"2011","edition":"3"},{"key":"bibr4-1090198114560019","doi-asserted-by":"publisher","DOI":"10.1080\/01635589209514201"},{"key":"bibr5-1090198114560019","doi-asserted-by":"publisher","DOI":"10.4135\/9781849209175"},{"key":"bibr6-1090198114560019","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"bibr7-1090198114560019","doi-asserted-by":"publisher","DOI":"10.1006\/appe.1995.0062"},{"key":"bibr8-1090198114560019","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-10-199905180-00017"},{"key":"bibr9-1090198114560019","doi-asserted-by":"publisher","DOI":"10.1023\/B:PREV.0000013980.12412.cd"},{"key":"bibr10-1090198114560019","unstructured":"Centers for Disease Control and Prevention. 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