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Data included demographics, disease and treatment status, HBM constructs (including perceived severity, perceived benefit, perceived barrier, cue to action, self-efficacy), social support (including family\u2019s, friends\u2019, and others\u2019 support), and willingness to participate. Statistical analyses involved factor analysis, reliability testing, correlations, and hierarchical regression. The mean willingness score was 2.883 (range = 1\u20135). Willingness varied significantly by living arrangements, employment, income, and treatments. Demographics explained 9.8% of the variance, disease and treatment status 12%, and social support 22.4%, with family support as a significant predictor (\u03b2 = 0.202,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; .001). Incorporating HBM constructs raised the explained variance to 48.2%. Key positive predictors included cues to action (\u03b2 = 0.251), self-efficacy (\u03b2 = 0.281), and perceived severity (\u03b2 = 0.151), while perceived barriers reduced willingness (\u03b2 = \u22120.114). Findings suggest Chinese cancer patients show limited willingness to join phase III trials, although it should be generalized cautiously, considering the non-representative nature of the online sample. Enhancing family support and targeting self-efficacy and external motivators may improve engagement, supporting the utility of the HBM framework.\n                  <\/jats:p>","DOI":"10.1177\/10901981261450599","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T12:06:06Z","timestamp":1781870766000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Chinese Cancer Patients\u2019 Willingness for Phase III Trials: Health Belief Model and Social Support"],"prefix":"10.1177","author":[{"given":"Tantan","family":"Cheng","sequence":"first","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanlin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuruo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingqi","family":"Han","sequence":"additional","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Hao","sequence":"additional","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinrui","family":"Shi","sequence":"additional","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2530-7204","authenticated-orcid":false,"given":"Jiwei","family":"Wang","sequence":"additional","affiliation":[{"name":"Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[{"name":"Shanghai General Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"crossref","unstructured":"Amin S. 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