{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T10:29:56Z","timestamp":1777717796524,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","issue":"3_suppl","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Cosmetic Ingredient Review"},{"name":"Personal Care Products Council"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Toxicol"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>The Expert Panel for Cosmetic Ingredient Safety (Panel) considered whether the safety of PEG Stearate ingredients as used in cosmetics should be reassessed. These ingredients are reported to function primarily as surfactants and emollients. The Panel reviewed newly available animal and human data related to these ingredients. The Panel concluded that the PEG Stearates are safe as cosmetic ingredients in the practices of use and concentrations described in the safety assessment.<\/jats:p>","DOI":"10.1177\/10915818251359230","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T13:47:53Z","timestamp":1757598473000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Re-Review Summary of PEG Stearates as Used in Cosmetics"],"prefix":"10.1177","volume":"44","author":[{"given":"Monice M.","family":"Fiume","sequence":"first","affiliation":[{"name":"Cosmetic Ingredient Review Senior Director"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilma F.","family":"Bergfeld","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald V.","family":"Belsito","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curtis D.","family":"Klaassen","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan E.","family":"Rettie","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Ross","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Slaga","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul W.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan C.","family":"Tilton","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart","family":"Heldreth","sequence":"additional","affiliation":[{"name":"Cosmetic Ingredient Review Executive Director"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/10915818309142000"},{"issue":"1","key":"e_1_3_3_3_2","first-page":"74","article-title":"Annual review of cosmetic ingredient safety assessments\u20142002\/2003. PEG-2, -3, -4, -5, -6, -6-32, -7, -8, -9, -10, -12, -14, -15, -18, -20, -23, -25, -30, -32, -35, -36, -40, -45, -50, -55, -75, -90, -100, -120, and -150 Stearates","volume":"24","author":"Andersen FA","year":"2005","unstructured":"Andersen FA. Annual review of cosmetic ingredient safety assessments\u20142002\/2003. PEG-2, -3, -4, -5, -6, -6-32, -7, -8, -9, -10, -12, -14, -15, -18, -20, -23, -25, -30, -32, -35, -36, -40, -45, -50, -55, -75, -90, -100, -120, and -150 Stearates. Int J Toxicol. 2005;24(S1):74-80.","journal-title":"Int J Toxicol"},{"key":"e_1_3_3_4_2","unstructured":"US Food and Drug Administration (FDA) Center for Food Safety & Applied Nutrition (CFSAN).Voluntary Cosmetic Registration Program - frequency of use of cosmetic ingredients. College Park MD [Obtained under the Freedom of Information Act from CFSAN; requested as \u201cFrequency of Use Data\u201d January 4 2023; received February 2 2023]; 2023."},{"key":"e_1_3_3_5_2","unstructured":"Personal Care Products Council. Concentration of use by FDA product category: PEG Stearates. [Unpublished data submitted by Personal Care Products Council on February 22 2023]; 2023."},{"key":"e_1_3_3_6_2","unstructured":"European Chemicals Agency (ECHA). ECHA Dossier: fatty acids C16-18 esters with diethylene glycol. CAS No. 85116-97-8; 2023. Date Accessed: Aug 2024."},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-011-9745-4"}],"container-title":["International Journal of Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10915818251359230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10915818251359230","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10915818251359230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:23:23Z","timestamp":1777458203000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10915818251359230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,11]]},"references-count":6,"journal-issue":{"issue":"3_suppl","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1177\/10915818251359230"],"URL":"https:\/\/doi.org\/10.1177\/10915818251359230","relation":{},"ISSN":["1091-5818","1092-874X"],"issn-type":[{"value":"1091-5818","type":"print"},{"value":"1092-874X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,11]]}}}