{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T03:00:20Z","timestamp":1785121220234,"version":"3.55.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"2_suppl","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Cosmetic Ingredient Review"},{"name":"Personal Care Products Council"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Toxicol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:p>The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 glycolactone ingredients. Glucoheptonolactone and Gluconolactone are reported to function in cosmetics as skin-conditioning agents\u2014miscellaneous, and Gluconolactone is also reported to function as a chelating agent. No functions are reported for the other 3 ingredients. The Panel considered the available data and concluded that Gluconolactone is safe in cosmetics in the present practices of use and concentration described in this safety assessment; however, the Panel concluded the available data are insufficient to make a determination that Galactonolactone, Glucarolactone, Glucoheptonolactone, and Ribonolactone are safe under the intended conditions of use in cosmetic formulations.<\/jats:p>","DOI":"10.1177\/10915818261455261","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:40:21Z","timestamp":1780728021000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Safety Assessment of Glycolactones as Used in Cosmetics"],"prefix":"10.1177","volume":"45","author":[{"given":"Priya","family":"Ferguson","sequence":"first","affiliation":[{"name":"Cosmetic Ingredient Review Associate Toxicologist\/Senior Scientific Analyst\/Writer"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilma F.","family":"Bergfeld","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald V.","family":"Belsito","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis D.","family":"Klaassen","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel C.","family":"Liebler","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan E.","family":"Rettie","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ross","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald C.","family":"Shank","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Slaga","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan C.","family":"Tilton","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monice M.","family":"Fiume","sequence":"additional","affiliation":[{"name":"Cosmetic Ingredient Review Senior Director"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Heldreth","sequence":"additional","affiliation":[{"name":"Cosmetic Ingredient Review Executive Director"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"International Cosmetic Ingredient Dictionary","author":"Personal Care Products Council","unstructured":"Personal Care Products Council. 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