{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:47:55Z","timestamp":1792068475188,"version":"4.4.0"},"reference-count":10,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Cosmetic Ingredient Review"},{"name":"Personal Care Products Council"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Toxicol"],"abstract":"<jats:p>The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Octyldodecyl Stearoyl Stearate. Octyldodecyl Stearoyl Stearate is reported to function in cosmetics as a skin conditioning and viscosity increasing agent. The Panel reviewed the relevant new data concerning the safety of this ingredient in cosmetic formulations, as well as data from previously published safety assessments, and concluded that Octyldodecyl Stearoyl Stearate is safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating.<\/jats:p>","DOI":"10.1177\/10915818261494996","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:02:20Z","timestamp":1791810140000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Final Amended Safety Assessment of Octyldodecyl Stearoyl Stearate as Used in Cosmetics"],"prefix":"10.1177","author":[{"given":"Regina","family":"Tucker","sequence":"first","affiliation":[{"name":"Cosmetic Ingredient Review Former Scientific Analyst\/Writer"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilma F.","family":"Bergfeld","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald V.","family":"Belsito","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis D.","family":"Klaassen","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan E.","family":"Rettie","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ross","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Slaga","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Former Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Expert Panel for Cosmetic Ingredient Safety Member"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan C.","family":"Tilton","sequence":"additional","affiliation":[{"name":"Cosmetic Ingredient Review Former Scientific Analyst\/Writer"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monice","family":"Fiume","sequence":"additional","affiliation":[{"name":"Cosmetic Ingredient Review Senior Director"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Heldreth","sequence":"additional","affiliation":[{"name":"Cosmetic Ingredient Review Executive Director"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Nikitakis J Kowcz A. 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Int J Toxicol. 2006;25(Suppl 2):73-78.","journal-title":"Int J Toxicol"},{"issue":"2","key":"e_1_3_3_7_2","first-page":"5S","article-title":"Safety assessment of alkyl esters as used in cosmetics","volume":"34","author":"Fiume MM","year":"2015","unstructured":"Fiume MM, Heldreth BA, Bergfeld WF, et al. Safety assessment of alkyl esters as used in cosmetics. Int J Toxdicol. 2015;34(2 Suppl):5S-69S.","journal-title":"Int J Toxdicol"},{"key":"e_1_3_3_8_2","unstructured":"U.S. Food and Drug Administration Center for Food Safety & Applied Nutrition (CFSAN). Voluntary Cosmetic Registration Program - Frequency of use of cosmetic ingredients. College Park MD. Obtained under the Freedom of Information Act from CFSAN; requested as \u201cFrequency of Use Data\u201d January 4 2023; received February 2 2023; 2023."},{"key":"e_1_3_3_9_2","unstructured":"European.Commission. CosIng database; following Cosmetic Regulation No. 1223\/2009. https:\/\/ec.europa.eu\/growth\/tools-databases\/cosing\/. 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