{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:30:19Z","timestamp":1777937419060,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Appendiceal stump closure is critical in laparoscopic appendectomy (LA) to prevent complications such as stump leakage and intra-abdominal abscess formation. This study aims to evaluate the safety and effectiveness of LigaSure\u2122 versus Endoloop for appendiceal stump closure in pediatric LA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This prospective multicenter comparative study included 199 pediatric patients who underwent LA between May 2021 and October 2023 at two pediatric surgery clinics. Patients were allocated to the LigaSure group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 74) or Endoloop group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 125) based on the surgeon\u2019s intraoperative preference. Data collected included demographic characteristics, laboratory and radiological findings, intraoperative details, postoperative complications, and histopathological measurements of appendiceal and lumen diameters. Statistical analyses were performed using the independent samples\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test and chi-square test, with significance at\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      No significant differences were observed between groups regarding age (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .670), gender (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .439), leukocyte count (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .072), or C-reactive protein levels (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .368). Complicated appendicitis was more prevalent in the LigaSure group (12.2%) compared to the Endoloop group (5.6%). No intra-abdominal abscesses or stump leakage were reported in either group. Histopathological analysis revealed no significant difference in mean appendiceal diameter (LigaSure: 8.9 \u00b1 0.2 mm; Endoloop: 8.9 \u00b1 0.1 mm;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .743) or lumen diameter (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .096). The largest lumen diameter measured in appendix specimens was 5113 \u03bcm, while the smallest was 255.6 \u03bcm (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .096). No cases of intra-abdominal abscess or stump leakage were reported. The mean hospital stay was comparable (LigaSure: 2 \u00b1 0.2 days; Endoloop: 2 \u00b1 0.1 days;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .068).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>LigaSure\u2122 is a safe and effective alternative to Endoloop for appendiceal stump closure in pediatric LA. The device\u2019s ability to provide a secure seal makes it a reliable option, even in cases of complicated appendicitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10926429251382515","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:19:57Z","timestamp":1759540797000},"page":"828-833","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Endoloop Versus LigaSure for Appendiceal Stump Closure in Pediatric Laparoscopic Appendectomy: A Multicenter Prospective Trial"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2178-2967","authenticated-orcid":false,"given":"\u015eenay","family":"Kurtulu\u015f","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, \u00c7anakkale Onsekiz Mart University, \u00c7anakkale, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alev","family":"S\u00fczen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neslihan","family":"Kaya Terzi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, \u00c7anakkale Onsekiz Mart University, \u00c7anakkale, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan Ya\u015far","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2014.02.031"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.3928\/00904481-20160525-01"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1021466"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2019.175"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.03.017"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2002.34998"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-1344-z"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-13-154"},{"issue":"1","key":"e_1_3_4_10_2","first-page":"17","article-title":"Intracorporeal knot-tying and suturing techniques in laparoscopic surgery: Technical details","volume":"4","author":"Croce E","year":"2000","unstructured":"Croce E, , Olmi S. 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