{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:54:35Z","timestamp":1790009675823,"version":"4.0.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Benign prostatic hyperplasia is a leading cause of lower urinary tract symptoms in aging men. When medical therapy fails, surgery is indicated. This study evaluates the safety and efficacy of Aquablation compared with transurethral resection of the prostate (TURP) and Holmium laser enucleation of the prostate (HoLEP) in patients with bladder outlet obstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Materials:<\/jats:title>\n                    <jats:p>A prospective analysis of 318 Aquablation patients (2023\u20132025) was conducted and compared with 83 TURP and 83 HoLEP patients from a retrospective database. Functional outcomes were assessed using International Prostate Symptom Score (IPSS), ICIQ-UI, EF-IIEF, and MSHQ-EJD SF. Complications were graded using the Clavien-Dindo classification. Follow-ups were performed at 3, 6, and 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Aquablation patients had larger prostates than TURP (94 versus 54.7 cc;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .0001) but smaller than HoLEP (105 cc;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .002) patients. More Aquablation patients had indwelling catheters and were on anticoagulants (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .0001). IPSS improvement was the greatest in Aquablation (18.9 points) versus TURP (13.8) and HoLEP (14.7;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .000). Erectile function was preserved in Aquablation (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .859), with significantly better ejaculatory function (82.8% preserved) than TURP (36%) and HoLEP (18%). Furthermore, Clavien-Dindo grade 1\u20132 complications were higher in Aquablation, but serious events (CD 3\u20134) were comparable. Complication rates declined significantly after the first 30 Aquablation cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Aquablation is an effective surgical option for medium to large prostates, offering superior symptom relief and preservation of sexual function. Although its learning curve is shorter than HoLEP\u2019s, proper training is essential to minimize early complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10926429251393894","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:46:21Z","timestamp":1762821981000},"page":"11-17","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Aquablation for Benign Prostatic Hyperplasia: A Prospective Study with Comparative Analysis of Transurethral Resection of the Prostate and Holmium Laser Enucleation"],"prefix":"10.1177","volume":"36","author":[{"given":"Dolev","family":"Perez","sequence":"first","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel","family":"Mamber","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Pasherstnik","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitry","family":"Koulikov","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ala Eddin","family":"Natsheh","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofer Z.","family":"Shenfeld","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilan Z.","family":"Kafka","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Hen","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Malinger","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avital","family":"Zeldin","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abd","family":"Shabaneh","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Qadan","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel A.","family":"Ostrovsky","sequence":"additional","affiliation":[{"name":"The Department of Anesthesiology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Chertin","sequence":"additional","affiliation":[{"name":"The Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(17)49698-4"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000001298"},{"issue":"5","key":"e_1_3_3_4_2","first-page":"S122","article-title":"BPH: Epidemiology and comorbidities","volume":"12","author":"McVary KT","year":"2006","unstructured":"McVary KT. BPH: Epidemiology and comorbidities. Am J Manag Care, 2006; 12(5 Suppl):S122\u2013S128.","journal-title":"Am J Manag Care"},{"key":"e_1_3_3_5_2","unstructured":"Gravas S Cornu JN Gacci M Drake MJ et al. EAU Guidelines on the Management of Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS) including Benign Prostatic Obstruction (BPO). European Association of Urology; 2024. Available at: https:\/\/d56bochluxqnz.cloudfront.net\/documents\/full-guideline\/EAU-Guidelines-on-Non-Neurogenic-Male-LUTS-2024.pdf"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.05.048"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9020603"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.042"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.5152\/tud.2021.21126"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2021.01.004"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14126"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.07.005"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-020-03137-8"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2021.04.004"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.12.065"},{"issue":"1","key":"e_1_3_3_16_2","first-page":"10960","article-title":"Five-year outcomes for Aquablation therapy compared to TURP: Results from a double-blind, randomized trial in men with LUTS due to BPH","volume":"29","author":"Gilling PJ","year":"2022","unstructured":"Gilling PJ, , Barber N, , Bidair M, et al. Five-year outcomes for Aquablation therapy compared to TURP: Results from a double-blind, randomized trial in men with LUTS due to BPH. 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