{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:57:01Z","timestamp":1790517421196,"version":"4.1.0"},"reference-count":44,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Laparoendoscopic &amp; Advanced Surgical Techniques"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Minimally invasive right colectomy is a standard treatment for Crohn\u2019s disease. Although intracorporeal anastomosis (ICA) has shown favorable outcomes in minimally invasive colorectal surgery, evidence specific to Crohn\u2019s disease remains limited. We performed the first systematic review and meta-analysis comparing ICA and extracorporeal anastomosis (ECA) in this setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science were searched from database inception through June 2026 for comparative studies evaluating ICA versus ECA in adult patients undergoing minimally invasive ileocecectomy or ileocolic resection for Crohn\u2019s disease. Random-effects meta-analyses were performed using odds ratios (ORs) or mean differences (MDs) with 95% confidence intervals (CIs). Risk of bias was assessed using ROBINS-I, and certainty of evidence was evaluated with the GRADE approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Four retrospective cohort studies involving 672 patients (186 ICA and 486 ECA) were analyzed. ICA significantly reduced overall postoperative complications compared with ECA (OR: 0.44, 95% CI: 0.28\u20130.70;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001;\n                      <jats:italic toggle=\"yes\">\n                        I\n                        <jats:sup>2<\/jats:sup>\n                        =\n                      <\/jats:italic>\n                      0%). Anastomotic leak, surgical site infection, 30-day readmission, length of hospital stay, clinical recurrence, endoscopic recurrence, and surgical recurrence were comparable between groups. Operative time was longer with ICA (MD 70.2 minutes, 95% CI: 55.2\u201385.2;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>ICA was associated with fewer postoperative complications than ECA during minimally invasive ileocolic resection for Crohn\u2019s disease, without increasing anastomotic failure, hospital stay, or disease recurrence, although operative time was longer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10926429261491060","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:47:49Z","timestamp":1790128069000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Intracorporeal Versus Extracorporeal Anastomosis in Minimally Invasive Ileocecectomy or Ileocolic Resection for Crohn\u2019s Disease: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","author":[{"given":"Beatriz Yukari","family":"Yokoyama","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Heliopolis Hospital, S\u00e3o Paulo-SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vict\u00f3ria Recidivi e.","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Heliopolis Hospital, S\u00e3o Paulo-SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Carvalho Lemos de Souza","family":"Aguiar","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Heliopolis Hospital, S\u00e3o Paulo-SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lder Santos","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Heliopolis Hospital, S\u00e3o Paulo-SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Monteiro","family":"Delgado","sequence":"additional","affiliation":[{"name":"Medical School of Federal University of Minas Gerais, Belo Horizonte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Theis","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Mazzola","family":"Poli de Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Bellotti","family":"Formiga","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Heliopolis Hospital, S\u00e3o Paulo-SP, Brazil."},{"name":"Department of Colorectal Surgery, Hospital of Santa Casa de Miseric\u00f3rdia, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2960-3810","authenticated-orcid":false,"given":"Bernardo Fontel","family":"Pompeu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Heliopolis Hospital, S\u00e3o Paulo-SP, Brazil."},{"name":"Department of Surgery USCS, University of S\u00e3o Caetano do Sul, S\u00e3o Paulo-SP, 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