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Over the course of 20 years, a definitive histopathologic diagnosis of GCM has been made at our institution in only two pediatric patients, and in neither instance was the diagnosis of GCM rendered on initial cardiac biopsy. We present the two patients and highlight the similarities in their clinical presentation and their challenging and inconclusive- albeit histologically similar- initial cardiac biopsy findings.<\/jats:p>","DOI":"10.1177\/10935266211044952","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T17:53:24Z","timestamp":1633370004000},"page":"197-202","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Giant Cell Myocarditis in Children: Elusive Giant Cells Might Not Be the Only Clue"],"prefix":"10.1177","volume":"25","author":[{"given":"Chrystalle Katte","family":"Carreon","sequence":"first","affiliation":[{"name":"Department of Pathology, Boston Children\u2019s Hospital and Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathon A.","family":"Hagel","sequence":"additional","affiliation":[{"name":"Department of 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