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We conclude that such cases often represent diagnostic challenges at the clinical and microscopic levels. We emphasize that awareness of this rare presentation of Hodgkin lymphoma is key to avoid diagnostic delay or interpretation pitfalls.<\/jats:p>","DOI":"10.1177\/10935266251326216","type":"journal-article","created":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T06:39:52Z","timestamp":1742020792000},"page":"304-309","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Classic Hodgkin Lymphoma With Primary Presentation as Lytic Bone Lesions and Pancytopenia: Report of a Pediatric Case and Review of Literature"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0706-8633","authenticated-orcid":false,"given":"Jacob","family":"Christofi","sequence":"first","affiliation":[{"name":"Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roopa","family":"Kodimyala","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Nationwide Children\u2019s Hospital, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Summit","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nationwide Children\u2019s Hospital, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8944-2128","authenticated-orcid":false,"given":"Samir B.","family":"Kahwash","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA"},{"name":"Department of Pathology and Laboratory Medicine, Nationwide Children\u2019s Hospital, Columbus, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"National Cancer Institute. 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