{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:35:31Z","timestamp":1777937731539,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100009898","name":"Defense Health Agency","doi-asserted-by":"publisher","award":["Clinical Investigator Program"],"award-info":[{"award-number":["Clinical Investigator Program"]}],"id":[{"id":"10.13039\/100009898","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>\n                    Mowat-Wilson Syndrome is an autosomal dominant disorder caused by de novo heterozygous mutations of\n                    <jats:italic toggle=\"yes\">ZEB2<\/jats:italic>\n                    on 2q22. It is characterized by developmental delay, Hirschsprung\u2019s disease, seizures, and a wide variety of malformations affecting the neurologic, cardiac, and genitourinary systems. Reports describing the findings of Mowat-Wilson Syndrome at autopsy are sparse. Case reports of suprasellar spindle cell lipomas are even rarer, a circumstance that contributes to uncertainty regarding their etiology as true neoplasms rather than congenital malformations. Here we report the gross, histopathologic, and molecular findings of a 4-year-old female with Mowat-Wilson Syndrome presenting with sepsis in the setting of otitis media and incidentally found to have a rare suprasellar spindle cell lipoma demonstrating loss of\n                    <jats:italic toggle=\"yes\">RB1<\/jats:italic>\n                    by immunohistochemistry, suggestive of a neoplastic etiology.\n                  <\/jats:p>","DOI":"10.1177\/10935266251331266","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T05:51:02Z","timestamp":1745473862000},"page":"316-320","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Neuropathologic Findings in Mowat-Wilson Syndrome at Autopsy, Including a Suprasellar Spindle Cell Lipoma"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8015-3554","authenticated-orcid":false,"given":"Couger","family":"Jimenez Jaramillo","sequence":"first","affiliation":[{"name":"Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA"},{"name":"Department of Pathology, San Antonio Military Medical Center, San Antonio, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Berman","sequence":"additional","affiliation":[{"name":"Department of Pathology, San Antonio Military Medical Center, San Antonio, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Department of Pathology, San Antonio Military Medical Center, San Antonio, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Brady","sequence":"additional","affiliation":[{"name":"Department of Pathology, San Antonio Military Medical Center, San Antonio, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Pathology, San Antonio Military Medical Center, San Antonio, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Clement","sequence":"additional","affiliation":[{"name":"Department of Pathology, San Antonio Military Medical Center, San Antonio, TX, 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