{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T02:57:08Z","timestamp":1794279428507,"version":"4.9.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>Bullous pemphigoid (BP) is a rare autoimmune blistering disorder in pediatric patients. Although various medications have been implicated as potential triggers, hypersensitivity reactions associated with Rivaroxaban, a direct Factor Xa inhibitor, are rarely documented. We present a case of an 8-year-old male who developed widespread BP after 3\u2009months of Rivaroxaban therapy. Histopathological and immunofluorescence findings confirmed the diagnosis. Discontinuation of Rivaroxaban and administration of systemic corticosteroids led to rapid clinical improvement. This case highlights Rivaroxaban-induced BP as a potential adverse reaction in children and underscores the need for awareness and prompt management of this rare but treatable condition.<\/jats:p>","DOI":"10.1177\/10935266251404122","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:30:13Z","timestamp":1766057413000},"page":"152-157","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Pediatric Bullous Pemphigoid Induced by Rivaroxaban: A Rare Case Report With Underlying Hereditary Hypercoagulability"],"prefix":"10.1177","volume":"29","author":[{"given":"Yen Hoang","family":"Phan","sequence":"first","affiliation":[{"name":"City Children\u2019s Hospital, Ho Chi Minh City, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9556-4049","authenticated-orcid":false,"given":"Phi Duong","family":"Nguyen","sequence":"additional","affiliation":[{"name":"City Children\u2019s Hospital, Ho Chi Minh City, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khanh Ngoc Minh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"City Children\u2019s Hospital, Ho Chi Minh City, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinh Thanh","family":"Phan","sequence":"additional","affiliation":[{"name":"City Children\u2019s Hospital, Ho Chi Minh City, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diem Kieu","family":"Ly","sequence":"additional","affiliation":[{"name":"City Children\u2019s Hospital, Ho Chi Minh City, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien Minh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"City Children\u2019s Hospital, Ho Chi Minh City, Viet Nam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"10","article-title":"Childhood bullous pemphigoid: a case report and literature review","volume":"6","author":"Wu KG","year":"2013","unstructured":"Wu KG, Chou CS, Hsu CL, Lee ML, et al. 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