{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:07:12Z","timestamp":1789052832931,"version":"build-2803163510"},"reference-count":12,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100020105","name":"VIVA Foundation for Children with Cancer","doi-asserted-by":"publisher","award":["KKH-PBST"],"award-info":[{"award-number":["KKH-PBST"]}],"id":[{"id":"10.13039\/100020105","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    Pleuropulmonary blastoma and hepatoblastoma are 2 well-recognized embryonal tumors of the thorax and liver respectively occurring in children. The simultaneous presentation of 2 or more pediatric embryonal tumors in the same patient is extremely rare. Specifically, cases of concomitant pleuropulmonary blastoma and hepatoblastoma in the same patient are extremely rare with only a single clinical case report published thus far. We report a case of a 25-month-old boy presenting with concomitant pleuropulmonary blastoma and hepatoblastoma, and describe the clinical, imaging, and histopathological findings. We additionally describe the underlying\n                    <jats:italic toggle=\"yes\">DICER1<\/jats:italic>\n                    alterations in both tumors. This is the first case described in Vietnam and only the second such case reported globally.\n                  <\/jats:p>","DOI":"10.1177\/10935266251413978","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T08:49:27Z","timestamp":1769071767000},"page":"541-546","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report of Concomitant Pleuropulmonary Blastoma and Hepatoblastoma in a 25-Month-Old Child With a Germline\n                    <i>DICER1<\/i>\n                    Pathogenic Variant"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4627-4523","authenticated-orcid":false,"given":"Diep Hong","family":"Pho","sequence":"first","affiliation":[{"name":"Vietnam National Children\u2019s Hospital, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thach Ngoc","family":"Hoang","sequence":"additional","affiliation":[{"name":"Vietnam National Children\u2019s Hospital, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan Ngoc","family":"Bui","sequence":"additional","affiliation":[{"name":"Vietnam National Children\u2019s Hospital, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngoc Thi Kim","family":"Le","sequence":"additional","affiliation":[{"name":"Vietnam National Children\u2019s Hospital, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian Yuan","family":"Goh","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, KK Women\u2019s and Children\u2019s Hospital, Singapore, Singapore"},{"name":"Duke-NUS Medical School, Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5244-4285","authenticated-orcid":false,"given":"Kenneth Tou En","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, KK Women\u2019s and Children\u2019s Hospital, Singapore, Singapore"},{"name":"Duke-NUS Medical School, Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1174334"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.17998\/jlc.2022.02.24"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.21037\/jgo.2018.01.08"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCR.0000000000000027"},{"key":"e_1_3_2_6_2","volume-title":"Beckwith-Wiedemann syndrome","author":"Shuman C","year":"2023","unstructured":"Shuman C, Kalish JM, Weksberg R. Beckwith-Wiedemann syndrome. GeneReviews; 2023."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.31285"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-1079-PAMLTI"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/children6080086"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12051918"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3476(96)70393-1"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29032"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000081"}],"container-title":["Pediatric and Developmental Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10935266251413978","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10935266251413978","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10935266251413978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:17:34Z","timestamp":1789049854000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10935266251413978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,22]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/10935266251413978"],"URL":"https:\/\/doi.org\/10.1177\/10935266251413978","relation":{},"ISSN":["1093-5266","1615-5742"],"issn-type":[{"value":"1093-5266","type":"print"},{"value":"1615-5742","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,22]]}}}