{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:37:24Z","timestamp":1793813844434,"version":"4.6.1"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Fetal hemorrhage (FH) is an important and difficult cause of death to recognize at perinatal autopsy. Existing literature is restricted to case reports and small case series, and none comprehensively describe both placental and autopsy findings. We sought to characterize fetal and placenta findings where the ultimate cause of death was determined to be FH to aid in the identification of these cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This is an autopsy series of perinatal deaths with fetomaternal hemorrhage (FMH) and FH into the amnionic sac. We included singleton pregnancies with Kleihauer Betke (KB) testing, and divided cases into 3 groups: FMH with \u226540% of fetal blood volume, FMH \u226439%, and suspected FH into the amnionic sac with negative KB test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We identified 20 cases from 691\u2009perinatal autopsies, 10 with FMH \u226540%, 5 with FMH \u226439%, and 5 suspected FH into the amnionic sac. Cases with FMH\u226540% were likely to have a normal placental weight, villous edema, and fetal hydrops. While FH into the amnionic sac was more likely to have a small placenta with disruption\/defect of fetal vessels, and less likely to have fetal hydrops.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study describes the differences and similarities between cases with FMH and FH in to the amnionic sac, and highlights the need for careful placenta and fetal autopsy examinations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10935266261458194","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:17:58Z","timestamp":1781669878000},"page":"646-653","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterizing Fetal Hemorrhage in a Perinatal Autopsy Cohort"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3875-738X","authenticated-orcid":false,"given":"Erica","family":"Price","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Endeavor Health, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunitha","family":"Suresh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Endeavor Health, USA"},{"name":"Department of Obstetrics and Gynecology, University of Chicago Pritzker School of Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0104-5107","authenticated-orcid":false,"given":"Linda M.","family":"Ernst","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Endeavor Health, USA"},{"name":"Department of Pathology, University of Chicago Pritzker School of Medicine, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003719"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001937"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181e7d975"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38629.587639.7C"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-9-22"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.path.2012.11.005"},{"key":"e_1_3_2_8_2","volume-title":"Kleihauer Betke Test","author":"Krywko DM","year":"2025","unstructured":"Krywko DM, Yarrarapu SNS, Shunkwiler SM. Kleihauer Betke Test. StatPearls; 2025."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2004.06.015"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/0031302031000150515"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2025.110914"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S510550"},{"issue":"2","key":"e_1_3_2_13_2","first-page":"184","article-title":"[Benckiser\u2019s hemorrhage. 2 case reports and a review of the literature]","volume":"22","author":"Heckel S","year":"1993","unstructured":"Heckel S, Weber P, Dellenbach P. [Benckiser\u2019s hemorrhage. 2 case reports and a review of the literature]. J Gynecol Obstet Biol Reprod. 1993;22(2):184-190.","journal-title":"J Gynecol Obstet Biol Reprod"},{"issue":"2","key":"e_1_3_2_14_2","first-page":"107","article-title":"Umbilical cord rupture: a case report and review of literature","volume":"52","author":"Naidu M","year":"2007","unstructured":"Naidu M, Nama V, Karoshi M, Kakumani V, Worth R. Umbilical cord rupture: a case report and review of literature. Int J Fertil Womens Med. 2007;52(2-3):107-110.","journal-title":"Int J Fertil Womens Med"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(78)90670-1"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.2350\/13-12-1419-OA.1"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/10935266211008444"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2015-0225-CC"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181da7929"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1986.tb00226.x"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181b8f6e4"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-025-02548-y"},{"issue":"5","key":"e_1_3_2_23_2","first-page":"422","article-title":"Ruptures of the umbilical cord with a case of intrapartum rupture of all three vessels","volume":"70","author":"Bowles HE","year":"1949","unstructured":"Bowles HE, Mc KR. Ruptures of the umbilical cord with a case of intrapartum rupture of all three vessels. Calif Med. 1949;70(5):422.","journal-title":"Calif Med"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318193beaf"},{"issue":"6","key":"e_1_3_2_25_2","first-page":"651","article-title":"Fetal exsanguination associated with antepartum hemorrhage","volume":"118","author":"Akhter MS","year":"1978","unstructured":"Akhter MS, Savior JF, Akhter IA, Deacon JS. Fetal exsanguination associated with antepartum hemorrhage. Can Med Assoc J. 1978;118(6):651-652, 657.","journal-title":"Can Med Assoc J"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90812-2"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.33878"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/144.suppl2.012"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/296463"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199203000-00013"}],"container-title":["Pediatric and Developmental Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10935266261458194","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10935266261458194","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10935266261458194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:17:11Z","timestamp":1793812631000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10935266261458194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,16]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/10935266261458194"],"URL":"https:\/\/doi.org\/10.1177\/10935266261458194","relation":{},"ISSN":["1093-5266","1615-5742"],"issn-type":[{"value":"1093-5266","type":"print"},{"value":"1615-5742","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,16]]}}}