{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T17:03:05Z","timestamp":1784653385421,"version":"3.55.0"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatr Dev Pathol"],"abstract":"<jats:p>A 19-month-old patient died suddenly and unexpectedly ~11\u2009months after hematopoietic stem cell transplantation (HSCT) for Hurler syndrome. Post-mortem examination revealed pulmonary air emboli that were attributed to extensive colonic pneumatosis intestinalis, an uncommon but reported complication of HSCT. Gas emboli are not just the result of trauma or decompression sickness but are more commonly iatrogenic in origin, resulting from the procedural-related introduction of air into the vascular system; pneumatosis intestinalis has rarely been associated with air emboli. Pathologists should be cognizant of unusual complications of HSCT and maintain a high index of suspicion for air embolization, even in a medically complex patient, to ensure optimal autopsy examination.<\/jats:p>","DOI":"10.1177\/10935266261466222","type":"journal-article","created":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T15:09:53Z","timestamp":1784473793000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Fatal Pulmonary Air Emboli Associated with Pneumatosis Intestinalis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0268-3679","authenticated-orcid":false,"given":"Laura S.","family":"Finn","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA"},{"name":"Department of Pathology and Laboratory Medicine, Perelman School of Medicine at The University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"DePasquale","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA"},{"name":"Department of Pathology and Laboratory Medicine, Perelman School of Medicine at The University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Camacho-Bydume","sequence":"additional","affiliation":[{"name":"Division of Pediatric Blood and Marrow Transplantation and Cellular Therapy"},{"name":"Joseph M. Sanzari Children\u2019s Hospital, Hackensack University Medical Center, Hackensack, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,19]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Abramov A Luks VL De Bie F Hwang R Allukian M3rd Nace GWJr. Pneumatosis intestinalis in children beyond the neonatal period: is it always benign? Pediatr Surg Int. 2022;38:399-407. https:\/\/doi.org\/10.1007\/s00383-021-05048-0","DOI":"10.1007\/s00383-021-05048-0"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","unstructured":"Kurbegov AC Sondheimer JM. Pneumatosis intestinalis in non-neonatal pediatric patients. Pediatrics. 2001;108:402-406. https:\/\/doi.org\/10.1542\/peds.108.2.402","DOI":"10.1542\/peds.108.2.402"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","unstructured":"Jung S Fehr S Harder-d\u2019Heureuse J Wiedenmann B Dignass AU. 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Long term disease burden post-transplantation: three decades of observations in 25 Hurler patients successfully treated with hematopoietic stem cell transplantation (HSCT). Orphanet J Rare Dis. 2021;16:60. https:\/\/doi.org\/10.1186\/s13023-020-01644-w","DOI":"10.1186\/s13023-020-01644-w"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","unstructured":"Korhonen K Lovvorn HN3rd Koyama T et al. Incidence risk factors and outcome of pneumatosis intestinalis in pediatric stem cell transplant recipients. Pediatr Blood Cancer. 2012;58:616-620. https:\/\/doi.org\/10.1002\/pbc.23242","DOI":"10.1002\/pbc.23242"},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","unstructured":"Bhamidipati PK Ghobadi A Bauer S DiPersio JF Pusic I. Conservative management of pneumatosis intestinalis after allogeneic hematopoietic SCT. 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