{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:42:18Z","timestamp":1790185338606,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Aeromonas<\/jats:italic>\n                      spp. are important human pathogens causing enteric disease or invasive infections commonly involving skin and soft tissue, biliary system, blood stream, and lung following aspiration. Only limited data regarding\n                      <jats:italic toggle=\"yes\">Aeromonas<\/jats:italic>\n                      spp. infections from the United States are available.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>\n                      This is a retrospective analysis of all infections caused by\n                      <jats:italic toggle=\"yes\">Aeromoas<\/jats:italic>\n                      spp. during a four-year period at a rural hospital in the Appalachian region. Data were retrieved from electronic medical records, including the microbiology database.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Between 10\/2018 and 12\/2022, 26 isolates of\n                      <jats:italic toggle=\"yes\">Aeromonas<\/jats:italic>\n                      spp. in 21 patients (14 m\/7 f) with a median age of 56 (range 0.1\u201386) years were identified. Six isolates were from blood cultures (four associated with biliary infections); 14 patients had soft-tissue infections, and one had acute cholecystitis. There were 18\n                      <jats:italic toggle=\"yes\">A. hydrophila\/A. caviae<\/jats:italic>\n                      isolates, two specimens grew\n                      <jats:italic toggle=\"yes\">A. sobria<\/jats:italic>\n                      , and one\n                      <jats:italic toggle=\"yes\">A. veronii<\/jats:italic>\n                      . In 10 cases,\n                      <jats:italic toggle=\"yes\">Aeromonas<\/jats:italic>\n                      spp. was the only isolated organism; 11 infections (52%) were polymicrobial. Isolated co-pathogens were gram-positive cocci (6), gram-negative rods (6), and anaerobes (2). Nine patients underwent interventions (n = 10), including wound debridement (3), endoscopic retrograde cholangiopancreatography (ERCP) (3), percutaneous cholecystostomy (2), and laparoscopic cholecystectomy (2). Preferred antibiotics were fluoroquinolones (5), 3\n                      <jats:sup>rd<\/jats:sup>\n                      \/4\n                      <jats:sup>th<\/jats:sup>\n                      generation cephalosporins (5), trimethoprim\/sulfamethoxazole (TMPS) (2), and doxycycline (2). All infections were successfully treated, and all patients are currently alive except one, who died from metastatic pancreatic cancer.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Aeromonas<\/jats:italic>\n                      spp. are rare clinical pathogens but are capable of causing severe infections. Most patients in this series had surgical infections. Surgeons need to be aware that the organism has a propensity for causing biliary infections.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10962964251389150","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T09:22:11Z","timestamp":1760692931000},"page":"68-72","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Experience with Invasive\n                    <i>Aeromonas<\/i>\n                    Infections at a Rural Hospital in the United States of America"],"prefix":"10.1177","volume":"27","author":[{"given":"Jimmy","family":"Henrichs","sequence":"first","affiliation":[{"name":"Meritus Health, Hagerstown, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridhar","family":"Gona","sequence":"additional","affiliation":[{"name":"Meritus Health, Hagerstown, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"George","sequence":"additional","affiliation":[{"name":"Meritus Health, Hagerstown, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Bonatti","sequence":"additional","affiliation":[{"name":"Meritus Health, Hagerstown, Maryland, USA."},{"name":"University of Maryland School of Medicine, Hagerstown, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00039-09"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8010129"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10482-023-01896-z"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1008870"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13028-020-0504-y"},{"issue":"7","key":"e_1_3_2_7_2","first-page":"622","article-title":"Improved glutaminate-starch-penicillin agar for the isolation and enumeration of Aeromonas hydrophila from seawater by membrane filtration","volume":"43","author":"Papapetropoulou M","year":"1995","unstructured":"Papapetropoulou M, , Rodopoulou G, , Giannoulaki E. 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