{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T15:26:44Z","timestamp":1787153204362,"version":"build-2736575974"},"reference-count":12,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Palliative Medicine"],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Monitoring data for anamorelin in pancreatic cancer are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To descriptively examine week-three documentation-derived dietary intake category, observed body weight, laboratory-derived prognostic nutritional index (PNI), and treatment continuation after anamorelin initiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively included week-three-evaluable patients with unresectable or recurrent pancreatic cancer who initiated anamorelin at a Japanese hospital (July 2021\u2013October 2024). Dietary intake category was derived from routine documentation. Paired changes used the Wilcoxon signed-rank test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among patients (\n                      <jats:italic toggle=\"yes\">N<\/jats:italic>\n                      = 40; PNI,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 39), dietary intake was classified as increased in 17, stable in 21, and decreased in 2. Median observed body weight was higher at week three than baseline (51.1 vs. 50.2 kg;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.026), whereas median PNI was lower (38.5 vs. 39.8;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.006). The median time-to-discontinuation was 60 days; 16 patients (40.0%) continued \u226584 days.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>These descriptive findings require cautious multidimensional interpretation; causal treatment effects cannot be inferred.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10966218261457190","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T06:29:27Z","timestamp":1780554567000},"page":"1287-1291","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Three-Week Monitoring After Anamorelin Initiation in Unresectable or Recurrent Pancreatic Cancer: Dietary Intake Category, Observed Body Weight, and Prognostic Nutritional Index"],"prefix":"10.1177","volume":"29","author":[{"given":"Banri","family":"Ogino","sequence":"first","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4920-5130","authenticated-orcid":false,"given":"Shinya","family":"Kajiura","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."},{"name":"Department of Medical Oncology and Palliative Medicine, Toyama University Hospital, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiko","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kawanaka","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiki","family":"Entani","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Sakumura","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurika","family":"Nakayama","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Ueda","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iori","family":"Motoo","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Ando","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, University of Toyama, Toyama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology and Palliative Medicine, Toyama University Hospital, Toyama, 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[Prognostic nutritional index in gastrointestinal surgery of malnourished cancer patients]. 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