{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:12:14Z","timestamp":1792977134131,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2013,1,15]],"date-time":"2013-01-15T00:00:00Z","timestamp":1358208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>The medical records of 45 cases (56 eyes) of feline eosinophilic keratoconjunctivitis (EKC) diagnosed between 2005 and 2011 were reviewed. Cats were included if a clinical diagnosis of EKC was recorded and eosinophils were found on corneal cytology. Median age at presentation was 5 years (interquartiles 5-9 years) for both males and females. Domestic shorthair was the predominant breed, accounting for 77.8% of the cats. The condition was unilateral in 75.6% of cases, with the superotemporal quadrant of the cornea the most frequently affected position (76.8% of eyes). A history of corneal ulceration was recorded in 37.8% of cases, and corneal ulcers were present at or before diagnosis in 66.7% of the cats. Eosinophils were found in 92.0% of conjunctival scrapings. We performed polymerase chain reaction (PCR) for feline herpesvirus type 1 (FHV-1) for 33\/45 cats. Viral DNA was detected in 54.5% of these cats. FHV-1 DNA was detected by PCR in 66.7% of cats with a history and\/or presence of a corneal ulcer at first presentation, which is significantly more than those with no corneal ulcer at any time (22.2% FHV-1 DNA detected). Our findings suggest that a corneal ulcer can be present prior to the development of eosinophilic keratitis. Further studies are mandatory to explore the role that FHV-1 could play in EKC-associated corneal ulceration.<\/jats:p>","DOI":"10.1177\/1098612x12472181","type":"journal-article","created":{"date-parts":[[2013,1,15]],"date-time":"2013-01-15T23:03:29Z","timestamp":1358291009000},"page":"661-666","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":41,"title":["Feline eosinophilic keratoconjunctivitis: a retrospective study of 45 cases (56 eyes)"],"prefix":"10.1177","volume":"15","author":[{"given":"Eric","family":"Dean","sequence":"first","affiliation":[{"name":"Vet-Oeil Ophthalmology Clinic, Lognes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Meunier","sequence":"additional","affiliation":[{"name":"Vet-Oeil Ophthalmology Clinic, Lognes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,1,15]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"21","article-title":"Chronic eosinophilic keratitis in the cat","volume":"9","author":"Brightman AH","year":"1979","unstructured":"Brightman AH, Vestre WA, Helper LC, et al. 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