{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T10:58:31Z","timestamp":1793444311495,"version":"4.5.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T00:00:00Z","timestamp":1360800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p>Xanthine urolithiasis was diagnosed in a 10-month-old intact female domestic shorthair cat presented with acute renal failure due to bilateral ureteral obstruction. Ultrasonography revealed the presence of multiple uroliths in both kidneys and ureters that were not detectable on previous survey radiographs. Medical management failed and ureteral obstruction persisted with no evidence of stone migration into the bladder. Bilateral ureterotomy with urolith removal was performed in order to relieve the obstruction. The cat recovered from surgery, and blood urea nitrogen and creatinine values decreased within normal limits 6 days postoperatively. Urolith analysis by infrared spectrometry determined xanthine composition, and a higher blood and urine concentration of hypoxanthine and xanthine was also found. At 1-year follow-up, the cat was free of clinical signs. However, ultrasonography of the abdomen revealed small-size calculi in both kidneys, despite the low protein diet intake. The very young age of the animal suggests a possible congenital xanthinuria.<\/jats:p>","DOI":"10.1177\/1098612x13477413","type":"journal-article","created":{"date-parts":[[2013,2,15]],"date-time":"2013-02-15T00:14:58Z","timestamp":1360887298000},"page":"911-916","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Xanthine urolithiasis causing bilateral ureteral obstruction in a 10-month-old cat"],"prefix":"10.1177","volume":"15","author":[{"given":"Lisa A","family":"Mestrinho","sequence":"first","affiliation":[{"name":"Veterinary Science Research Centre (CICV), Faculty of Veterinary Medicine, Lus\u00f3fona University, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Technical University of Lisbon, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro B","family":"Parreira","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Center \u2018Refer\u00eancia Veterin\u00e1ria\u2019 Manique, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria MRE","family":"Niza","sequence":"additional","affiliation":[{"name":"Interdisciplinary Research Centre for Animal Health (CIISA), Faculty of Veterinary Medicine, Technical University of Lisbon, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annick J","family":"Hamaide","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, School of Veterinary Medicine, University of Li\u00e8ge, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,2,14]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1997.tb03470.x"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2007.03.012"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.164.3.91"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.932"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.937"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2011.00628.x"},{"key":"e_1_3_3_8_2","volume-title":"Proceedings UC Davis Urological Colloquium","author":"Osborne CA","unstructured":"Osborne CA, Lulich JP, Lekcharoensuk C, et al. Mineral composition of canine uroliths: current status (abstract). In: Proceedings UC Davis Urological Colloquium, Davis, CA, USA, 4\u20136 May 2000."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011686315522"},{"key":"e_1_3_3_10_2","volume-title":"Small animal clinical nutrition","author":"Osborne CA","year":"2010","unstructured":"Osborne CA, Bartges JW, Lulich JP, et al. Canine purine urolithiasis: causes, detection, management and prevention. In: Hand MS, Thatcher CD, Remillard RL, et al. (eds). Small animal clinical nutrition. 5th ed. Topeka: Mark Morris Institute, 2010; pp 883\u2013840.","edition":"5"},{"key":"e_1_3_3_11_2","first-page":"1781","volume-title":"The metabolic and molecular bases of inherited disease","author":"Simmonds HA","year":"1995","unstructured":"Simmonds HA, Reiter S, Nishino T. Hereditary xanthinuria. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds). The metabolic and molecular bases of inherited disease. 7th ed. New York: McGraw-Hill, 1995, pp 1781\u20131797.","edition":"7"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1997.58.02.118"},{"key":"e_1_3_3_13_2","volume-title":"Proceedings of the 21st American College of Veterinary Internal Medicine Forum","author":"Osborne CA","unstructured":"Osborne CA, Lulich JP, Lekcharoensuk CL, et al. Feline xanthine urolithiasis: a newly recognized cause of feline lower urinary tract disease. 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