{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T04:17:43Z","timestamp":1793679463568,"version":"4.5.1"},"reference-count":43,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2014,1,20]],"date-time":"2014-01-20T00:00:00Z","timestamp":1390176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Anaplasma platys<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">Apl<\/jats:italic>\n                    ), \u2018\n                    <jats:italic toggle=\"yes\">Candidatus<\/jats:italic>\n                    Mycoplasma haemominutum\u2019 (\n                    <jats:italic toggle=\"yes\">C<\/jats:italic>\n                    Mh),\n                    <jats:italic toggle=\"yes\">Bartonella henselae<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">Bh<\/jats:italic>\n                    ) and\n                    <jats:italic toggle=\"yes\">Bartonella koehlerae<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">Bk<\/jats:italic>\n                    ) were confirmed by polymerase chain reaction (PCR) amplification and DNA sequencing in a cat diagnosed with multiple myeloma. Other inconsistently documented hematologic abnormalities included anemia, thrombocytopenia, eosinophilia and hypoglycemia. Persistent\n                    <jats:italic toggle=\"yes\">Apl<\/jats:italic>\n                    infection was confirmed for the first time in a North American cat by sequencing three bacterial genes (\n                    <jats:italic toggle=\"yes\">16S<\/jats:italic>\n                    rRNA,\n                    <jats:italic toggle=\"yes\">p44<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">GroEL<\/jats:italic>\n                    ) in peripheral blood samples collected 100 days apart. Following doxycycline treatment for\n                    <jats:italic toggle=\"yes\">Apl<\/jats:italic>\n                    , multiple myeloma was diagnosed based upon a monoclonal gammopathy and splenic plasmacytosis, and the cat was treated with melphalan, chlorambucil and prednisolone.\n                    <jats:italic toggle=\"yes\">Apl<\/jats:italic>\n                    DNA was not amplified from post-treatment blood samples and the hyperglobulinemia resolved temporarily following chemotherapy. Retrospective PCR analysis of stored DNA extracts identified\n                    <jats:italic toggle=\"yes\">C<\/jats:italic>\n                    Mh,\n                    <jats:italic toggle=\"yes\">Bk<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Bh<\/jats:italic>\n                    infections. Retrospective PCR for antigen receptor rearrangements (PARR) of splenic aspirates did not confirm B- or T-cell clonality. Co-infection with multiple vector-borne pathogens should be a diagnostic consideration in cats with chronic hypergammaglobulinemia, monoclonal gammopathy and splenic plasmacytosis.\n                  <\/jats:p>","DOI":"10.1177\/1098612x13519632","type":"journal-article","created":{"date-parts":[[2014,1,20]],"date-time":"2014-01-20T21:58:05Z","timestamp":1390255085000},"page":"713-720","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["Co-infection with\n                    <i>Anaplasma platys, Bartonella henselae, Bartonella koehlerae<\/i>\n                    and \u2018\n                    <i>Candidatus<\/i>\n                    Mycoplasma haemominutum\u2019 in a cat diagnosed with splenic plasmacytosis and multiple myeloma"],"prefix":"10.1177","volume":"16","author":[{"given":"Barbara A","family":"Qurollo","sequence":"first","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University (NCSU), Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandhakumar","family":"Balakrishnan","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University (NCSU), Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coralie Zegre","family":"Cannon","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University (NCSU), Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo G","family":"Maggi","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University (NCSU), Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward B","family":"Breitschwerdt","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University (NCSU), Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,1,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2007.01.010"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.6.2651-2655.2005"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-3-76"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-3-33"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb01944.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2011.00811.x"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.42-5-596"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2004.12.005"},{"key":"e_1_3_3_10_2","first-page":"335","article-title":"Monoclonal gammopathy and lymphoma in a cat infected with feline immunodeficiency virus","volume":"27","author":"Rosenberg MP","year":"1991","unstructured":"Rosenberg MP, Hohenhaus AE, Matus RE. 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