{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T10:44:27Z","timestamp":1792579467555,"version":"4.5.0"},"reference-count":54,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objectives of this retrospective study were to investigate the actual incidence of postobstructive diuresis after relief of urethral obstruction in cats, as well as to identify changes in blood and urine parameters that might be associated with postobstructive diuresis (POD), and to assess the impact of fluid therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The medical records of 57 male cats with urethral obstruction that were treated with an indwelling urinary catheter were retrospectively analysed. Absolute urine output in ml\/kg\/h every 4 h and the incidence of cats with polyuria (urine volume &gt;2 ml\/kg\/h) at any time point over a 48 h period after the re-establishment of urine flow were investigated. In addition, postobstructive diuresis in relation to fluid therapy (POD\n                      <jats:sub>FR<\/jats:sub>\n                      ) was defined as urine output greater than the administered amount of intravenous fluids on at least two subsequent time points. Polyuria and POD\n                      <jats:sub>FR<\/jats:sub>\n                      were investigated for their association with blood and urine laboratory parameters.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 4 h, 74.1% (40\/54) of the cats had polyuria, with a urine output of &gt;2 ml\/kg\/h. Metabolic acidosis was present in 46.2% of the cats. Venous blood pH and bicarbonate were inversely correlated with urine output in ml\/kg\/h after 4 h. The overall incidence of POD within 48 h of catheterisation was 87.7%. There was a significant correlation between intravenous fluid rate at time point\n                      <jats:italic toggle=\"yes\">x<\/jats:italic>\n                      and urine output at time point\n                      <jats:italic toggle=\"yes\">x<\/jats:italic>\n                      + 1 at all the time points except for the fluid rate at time point 0 and the urine output after 4 h. POD\n                      <jats:sub>FR<\/jats:sub>\n                      was seen in 21\/57 cats (36.8%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>\n                      POD is a frequent finding in cats treated for urethral obstruction, and can be very pronounced. Further studies are required to determine whether or not a change in venous blood pH actually interferes with renal concentrating ability. The discrepancy between the frequency of cats with polyuria and POD\n                      <jats:sub>FR<\/jats:sub>\n                      (87.7% vs 36.8%) in the present study indicates that administered intravenous fluid therapy might be the driving force for the high incidence of polyuria in some cats with naturally occurring obstructive feline lower urinary tract disease.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x15594842","type":"journal-article","created":{"date-parts":[[2015,7,15]],"date-time":"2015-07-15T21:50:32Z","timestamp":1436997032000},"page":"809-817","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Postobstructive diuresis in cats with naturally occurring lower urinary tract obstruction: incidence, severity and association with laboratory parameters on admission"],"prefix":"10.1177","volume":"18","author":[{"given":"Laura","family":"Fr\u00f6hlich","sequence":"first","affiliation":[{"name":"Clinic of Small Animal Medicine, LMU Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, LMU Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola","family":"Sautter-Louis","sequence":"additional","affiliation":[{"name":"Clinic for Ruminants with Ambulatory and Herd Health Services, LMU Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roswitha","family":"Dorsch","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, LMU Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.221.502"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2004.12.001"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1978.172.07.801"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2005.tb00288.x"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2004.08.006"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108167"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.03.004"},{"key":"e_1_3_2_9_2","first-page":"201","article-title":"Acid-base and biochemical stabilization and quality of recovery in male cats with urethral obstruction and anesthetized with propofol or a combination of ketamine and diazepam","volume":"76","author":"Freitas GC","year":"2012","unstructured":"Freitas GC, da Cunha MG, Gomes K, et al. 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