{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:36:24Z","timestamp":1790422584269,"version":"4.1.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,7,9]],"date-time":"2016-07-09T00:00:00Z","timestamp":1468022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2017,2]]},"abstract":"\n Objectives<\/jats:title>\n Gonadotropin-releasing hormone (GnRH) agonists like deslorelin are being increasingly used in tom cats for their efficacy in controlling reproductive behaviour and fertility. Deslorelin implants have been widely available in Europe since 2008. Little, if anything, is known about the interval between treatment and onset of sterility, as well as semen quality, after treatment in tom cats. The purpose of this study was to investigate semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Fifteen healthy adult tom cats were treated with a 9.4 mg deslorelin implant (Suprelorin 12). For each cat, semen collection and a GnRH stimulation test (intramuscular administration of 50 \u03bcg gonadorelin [Fertagyl], followed by blood sampling 1 h later, to assay serum testosterone) were performed on the first consultation and then repeated every 15 days until complete sterility was achieved. Semen collection was performed by introducing a 14 cm, open-end feline catheter (Argyle) 9 cm into the distal urethra 10 mins after sedation by intramuscular injection of 100 \u03bcg\/kg medetomidine (Domitor).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Semen collection was not successful in all cats at each attempt. In the first month after treatment, the semen of only four cats could be evaluated, while the semen of eight cats could be evaluated during the second and third months of the study. Semen quality (ejaculate volume, progressive motility and morphological abnormalities) improved slightly during the first 19\u201325 days in 2\/4 cats, and in 1\/4 cats motility was still very high (80%) 25 days post-treatment (PT), but we have no data regarding fertility prior to treatment in this cat. The last cat never produced spermatozoa. Subsequently, semen quality gradually worsened in all cats from 30 days onwards. At 70 days PT, one cat was still potentially fertile. After 72 days all cats were sterile.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and relevance<\/jats:title>\n Semen quality increased slightly in treated cats during the first month after treatment, and then gradually decreased over the following months. Complete sterility was reached within 40\u201372 days following implantation.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1098612x15623985","type":"journal-article","created":{"date-parts":[[2016,1,13]],"date-time":"2016-01-13T20:27:25Z","timestamp":1452716845000},"page":"194-199","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant"],"prefix":"10.1177","volume":"19","author":[{"given":"Stefano","family":"Romagnoli","sequence":"first","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Baldan","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Righetti","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Milani","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Mollo","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calogero","family":"Stelletta","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,9]]},"reference":[{"key":"bibr1-1098612X15623985","first-page":"255","volume":"57","author":"Trigg TE","year":"2001","journal-title":"J Reprod Fertil Suppl"},{"key":"bibr2-1098612X15623985","doi-asserted-by":"publisher","DOI":"10.1071\/RD03039"},{"key":"bibr3-1098612X15623985","doi-asserted-by":"publisher","DOI":"10.1111\/rda.12058"},{"key":"bibr4-1098612X15623985","first-page":"686","volume-title":"Proceedings of the World Small Animal Veterinary Association Congress 2006","author":"Romagnoli S."},{"key":"bibr5-1098612X15623985","first-page":"9","volume":"26","author":"Pisu M","year":"2012","journal-title":"Veterinaria"},{"key":"bibr6-1098612X15623985","first-page":"198","volume":"20","author":"Sojka N","year":"1970","journal-title":"Lab Anim Care"},{"key":"bibr7-1098612X15623985","first-page":"156","volume":"9","author":"Zambelli D","year":"2011","journal-title":"Atti del IX Congr Naz SIRA"},{"key":"bibr8-1098612X15623985","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod29.4.1019"},{"key":"bibr9-1098612X15623985","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-72185-4_4"},{"key":"bibr10-1098612X15623985","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2010.10.020"},{"key":"bibr11-1098612X15623985","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2014.01.015"},{"key":"bibr12-1098612X15623985","unstructured":"Ackermann C, Trevisol E, Destro F. Deslorelin acetate (Suprelorin\u00ae) effects in semen quality of domestic cats. http:\/\/www.ivis.org\/proceedings\/iscfr\/2012\/1.pdf?LA=1 (2012, accessed December 11, 2015)."}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X15623985","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1098612X15623985","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X15623985","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:12:13Z","timestamp":1777500733000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X15623985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,9]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1177\/1098612X15623985"],"URL":"https:\/\/doi.org\/10.1177\/1098612x15623985","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,9]]}}}