{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:56:01Z","timestamp":1793228161045,"version":"4.5.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2017,4]]},"abstract":"\n Objectives<\/jats:title>\n \n Our objective was to perform the first multicentric study in Spain to evaluate the prevalence of feline herpesvirus-1 (FHV-1), feline calicivirus (FCV),\n Chlamydophila felis<\/jats:italic>\n and\n Mycoplasma felis<\/jats:italic>\n in cats with upper respiratory tract disease (URTD), conjunctivitis and\/or gingivostomatitis (GS) compared with control cats; and to evaluate risk factors for these clinical conditions.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Conjunctival and oropharyngeal swabs were collected and a questionnaire regarding signalment, lifestyle, vaccination history and clinical signs was obtained for each cat. Swabs were tested for each pathogen by real-time PCR.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The study population consisted of 358 cats, including 98 control cats. Among the 260 diseased cats, 127 cats presented with URTD, 149 cats had conjunctivitis, 154 cats were suffering GS; many cats presented more than one clinical condition. The prevalence observed of FHV-1, FCV,\n C felis<\/jats:italic>\n and\n M felis<\/jats:italic>\n was, respectively, 28.3%, 48.0%, 20.5% and 46.5% in cats with URTD; 24.2%, 43.6%, 19.5% and 38.3% in cats with conjunctivitis; and 15.6%, 58.4%, 9.1% and 37.7% in cats with GS. Prevalences in the control group were 6.1%, 15.3%, 2.0% and 20.4%, respectively. Coinfections were common among all groups of cats. Risk factors were identified for all groups. FHV-1, FCV and\n C felis<\/jats:italic>\n were associated with URTD and conjunctivitis. FCV was strongly associated with GS.\n M felis<\/jats:italic>\n was present in a high percentage of the population in all groups, but its role in these clinical conditions remains uncertain. Vaccination was protective for URTD and GS but not for conjunctivitis.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions and relevance<\/jats:title>\n \n This epidemiological study describes, for the first time, prevalence for FHV-1, FCV,\n C felis<\/jats:italic>\n and\n M felis<\/jats:italic>\n in Spain. In general, the prevalences found are similar to those reported in other countries. Factors associated with disease expression were also identified, which are relevant for practitioners.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1098612x16634387","type":"journal-article","created":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T22:09:20Z","timestamp":1456524560000},"page":"461-469","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":83,"title":["Prevalence of feline herpesvirus-1, feline calicivirus,\n Chlamydophila felis<\/i>\n and\n Mycoplasma felis<\/i>\n DNA and associated risk factors in cats in Spain with upper respiratory tract disease, conjunctivitis and\/or gingivostomatitis"],"prefix":"10.1177","volume":"19","author":[{"given":"Mireia","family":"Fernandez","sequence":"first","affiliation":[{"name":"Hospital Foundation Veterinary Clinic, Autonomous University of Barcelona, Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar G","family":"Manzanilla","sequence":"additional","affiliation":[{"name":"Hospital Foundation Veterinary Clinic, Autonomous University of Barcelona, Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Lloret","sequence":"additional","affiliation":[{"name":"Hospital Foundation Veterinary Clinic, Autonomous University of Barcelona, Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Merial Laboratories, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Thibault","sequence":"additional","affiliation":[{"name":"Merial SAS, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2011.07.006"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.05.003"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.05.004"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ctsap.2004.12.018"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.5326\/0380111"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.68.6.643"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2012.11.016"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2003.tb00140.x"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302X.2003.00033.x"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.10.007"},{"key":"e_1_3_3_12_2","first-page":"369","article-title":"Relevance of feline calicivirus, feline immunodeficiency virus, feline leukemia virus, feline herpesvirus and Bartonella henselae in cats with chronic gingivostomatitis","volume":"123","author":"Belgard S","year":"2010","unstructured":"Belgard S, Truyen U, Thibault JC, et al. Relevance of feline calicivirus, feline immunodeficiency virus, feline leukemia virus, feline herpesvirus and Bartonella henselae in cats with chronic gingivostomatitis. 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